STK4 Products
(serine/threonine Kinase 4 (STK4))
Categories
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008].
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Featured STK4 Categories
STK4 Antibodies
High quality antibodies with extensive validation data.
STK4 ELISA Kits
Reliable ELISA kits for a wide range of species.
STK4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended STK4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (8)
Cat. No.
ABIN563051
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IF, IHC (p), ICC
Validations
- (5)
Cat. No.
ABIN2856667
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN563050
Quantity
100 μg
Datasheet
Datasheet
Recommended STK4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889361
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6231399
Quantity
96 tests
Datasheet
Datasheet
Recommended STK4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321708
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321706
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7317074
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our STK4 products
: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).: "Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 3, pp. M110.001784, (2011) (PubMed).
: "Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 35029-38, (2010) (PubMed).
: "Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells." in: Cancer research, Vol. 68, Issue 7, pp. 2266-74, (2008) (PubMed).
: "Merlin is a potent inhibitor of glioma growth." in: Cancer research, Vol. 68, Issue 14, pp. 5733-42, (2008) (PubMed).
: "Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma." in: Molecular carcinogenesis, Vol. 46, Issue 10, pp. 865-71, (2007) (PubMed).
: "Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30836-44, (2007) (PubMed).
: "The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1." in: The EMBO journal, Vol. 26, Issue 21, pp. 4523-34, (2007) (PubMed).
Synonyms and alternative names related to STK4
serine/threonine kinase 4 (STK4), serine/threonine kinase 4 (Stk4), serine/threonine kinase 4 S homeolog (stk4.S), AI447339, AU020804, Kas-2, KRS2, krs2, MST1, Mst1, mst1, TIIAC, YSK3, Ysk3, ysk3Protein level used designations for STK4
- MST-1
- STE20-like kinase MST1
- dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2))
- kinase responsive to stress 2
- mammalian STE20-like protein kinase 1
- mammalian sterile 20-like 1
- serine/threonine-protein kinase 4
- serine/threonine-protein kinase Krs-2
- Yeast Sps1/Ste20-related kinase 3
- sterile 20-like kinase 1
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