STING/TMEM173 Products
(Transmembrane Protein 173 (TMEM173))
Categories
Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double- stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti- viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured STING/TMEM173 Categories
STING/TMEM173 Antibodies
High quality antibodies with extensive validation data.
STING/TMEM173 ELISA Kits
Reliable ELISA kits for a wide range of species.
STING/TMEM173 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended STING/TMEM173 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7439447
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (8)
Cat. No.
ABIN6220283
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (9)
Cat. No.
ABIN1501428
Quantity
100 μL
Datasheet
Datasheet
Recommended STING/TMEM173 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970832
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960146
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999504
Quantity
96 tests
Datasheet
Datasheet
Recommended STING/TMEM173 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125482
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7092708
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN6573465
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our STING/TMEM173 products
: "The deubiquitinase CYLD is a specific checkpoint of the STING antiviral signaling pathway." in: PLoS pathogens, Vol. 14, Issue 11, pp. e1007435, (2019) (PubMed).: "The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus." in: Cell reports, Vol. 26, Issue 9, pp. 2377-2393.e13, (2019) (PubMed).
: "STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade." in: The Journal of clinical investigation, Vol. 130, pp. 4350-4364, (2019) (PubMed).
: "Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents." in: Oncotarget, Vol. 7, Issue 47, pp. 77205-77224, (2018) (PubMed).
: "Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses." in: Nature communications, Vol. 9, Issue 1, pp. 125, (2018) (PubMed).
: "HPV18 Persistence Impairs Basal and DNA Ligand-Mediated IFN-β and IFN-λ1 Production through Transcriptional Repression of Multiple Downstream Effectors of Pattern Recognition Receptor Signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2076-2089, (2018) (PubMed).
: "PARP1 depletion induces RIG-I-dependent signaling in human cancer cells." in: PLoS ONE, Vol. 13, Issue 3, pp. e0194611, (2018) (PubMed).
: "UBXN3B positively regulates STING-mediated antiviral immune responses." in: Nature communications, Vol. 9, Issue 1, pp. 2329, (2018) (PubMed).
: "RAD51 interconnects between DNA replication, DNA repair and immunity." in: Nucleic acids research, Vol. 45, Issue 8, pp. 4590-4605, (2017) (PubMed).
: "Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway." in: Nature structural & molecular biology, Vol. 24, Issue 12, pp. 1124-1131, (2017) (PubMed).
Synonyms and alternative names related to STING/TMEM173
transmembrane protein 173 (TMEM173), transmembrane protein 173 (Tmem173), 2610307O08Rik, ERIS, MITA, Mita, MPYS, NET23, RGD1562552, STINGProtein level used designations for STING/TMEM173
- transmembrane protein 173
- N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner
- STING1
- endoplasmic reticulum IFN stimulator
- endoplasmic reticulum interferon stimulator
- hMITA
- hSTING
- mediator of IRF3 activation
- mitochondrial mediator of IRF3 activation
- stimulator of interferon genes protein
- MMITA
- mSTING
- Stimulator of interferon genes protein
- mitochondrial transmembrane protein 173
Did you look for something else?
- Stim2
- STIM1
- STIL
- STHA
- STH
- sTfR
- Sterol Regulatory Element Binding Proteins
- Sterol Carrier Protein 2
- Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
- Stereocilin
- STELLAR/DPPA3
- STELLAR
- Stefin A8
- Stefin A3
- Stefin A2
- Stearoyl-Coenzyme A Desaturase 1
- STEAP4
- STEAP3
- STEAP2
- STEAP1B
You are here:
