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Stim2 Products

(Stromal Interaction Molecule 2 (Stim2))

Categories

This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing. [provided by RefSeq, Dec 2009].

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Featured Stim2 Categories

Stim2 Antibodies

High quality antibodies with extensive validation data.

Stim2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Stim2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7270611
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7170837
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN656476
Quantity 400 μL
Datasheet Datasheet

Recommended Stim2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207815
Quantity 96 tests
Datasheet Datasheet

Recommended Stim2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2732853
Quantity 20 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751619
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our Stim2 products

Stathopulos, Zheng, Ikura: "Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics." in: The Journal of biological chemistry, Vol. 284, Issue 2, pp. 728-32, (2009) (PubMed).

Lefkimmiatis, Srikanthan, Maiellaro, Moyer, Curci, Hofer: "Store-operated cyclic AMP signalling mediated by STIM1." in: Nature cell biology, Vol. 11, Issue 4, pp. 433-42, (2009) (PubMed).

DeHaven, Jones, Petranka, Smyth, Tomita, Bird, Putney: "TRPC channels function independently of STIM1 and Orai1." in: The Journal of physiology, Vol. 587, Issue Pt 10, pp. 2275-98, (2009) (PubMed).

Luik, Lewis: "New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells." in: Trends in molecular medicine, Vol. 13, Issue 3, pp. 103-7, (2007) (PubMed).

Wedel, Boyles, Putney, Bird: "Role of the store-operated calcium entry proteins Stim1 and Orai1 in muscarinic cholinergic receptor-stimulated calcium oscillations in human embryonic kidney cells." in: The Journal of physiology, Vol. 579, Issue Pt 3, pp. 679-89, (2007) (PubMed).

Soboloff, Spassova, Hewavitharana, He, Xu, Johnstone, Dziadek, Gill: "STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ Entry." in: Current biology : CB, Vol. 16, Issue 14, pp. 1465-70, (2006) (PubMed).

Spassova, Soboloff, He, Xu, Dziadek, Gill: "STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 11, pp. 4040-5, (2006) (PubMed).

Zhang, Yu, Roos, Kozak, Deerinck, Ellisman, Stauderman, Cahalan: "STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane." in: Nature, Vol. 437, Issue 7060, pp. 902-5, (2005) (PubMed).

Navas-Martín, Weiss: "Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development." in: Journal of neurovirology, Vol. 10, Issue 2, pp. 75-85, (2004) (PubMed).

Synonyms and alternative names related to Stim2

stromal interaction molecule 2 (STIM2), stromal interaction molecule 2 (stim2), stromal interaction molecule 2 (Stim2), STIM2

Protein level used designations for Stim2

  • stromal interaction molecule 2
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