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STIL Products

(SCL/TAL1 Interrupting Locus (STIL))

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This gene encodes a cytoplasmic protein implicated in regulation of the mitotic spindle checkpoint, a regulatory pathway that monitors chromosome segregation during cell division to ensure the proper distribution of chromosomes to daughter cells. The protein is phosphorylated in mitosis and in response to activation of the spindle checkpoint, and disappears when cells transition to G1 phase. It interacts with a mitotic regulator, and its expression is required to efficiently activate the spindle checkpoint. It is proposed to regulate Cdc2 kinase activity during spindle checkpoint arrest. Chromosomal deletions that fuse this gene and the adjacent locus commonly occur in T cell leukemias, and are thought to arise through illegitimate V-(D)-J recombination events. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured STIL Categories

STIL Antibodies

High quality antibodies with extensive validation data.

Recommended STIL Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7168626
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IHC (p)
Validations
  • (1)
Cat. No. ABIN1387013
Quantity 100 μL
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN6244213
Quantity 200 μL
Datasheet Datasheet

Recommended STIL Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095690
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135331
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to STIL

STIL, centriolar assembly protein (Stil), STIL, centriolar assembly protein (STIL), Scl/Tal1 interrupting locus (Stil), STIL, centriolar assembly protein L homeolog (stil.L), scl/tal1 interrupting locus (stil), chunp6907, MCPH7, Sil, SIL, sill, zgc:110502

Protein level used designations for STIL

  • Tal1 interrupting locus
  • SCL-interrupting locus protein
  • TAL-1-interrupting locus protein
  • SCL-interrupting locus protein homolog
  • TAL1 (SCL) interrupting locus like
  • cassiopeia
  • csp
  • nbb
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