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STEAP3 Products

(STEAP Family Member 3, Metalloreductase (STEAP3))

Categories

Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Also mediates reduction of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

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Featured STEAP3 Categories

STEAP3 Antibodies

High quality antibodies with extensive validation data.

STEAP3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STEAP3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7159505
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6265332
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3021068
Quantity 100 μL
Datasheet Datasheet

Recommended STEAP3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648021
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232485
Quantity 96 tests
Datasheet Datasheet

Recommended STEAP3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505333
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3115556
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3126070
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our STEAP3 products

Lane, Chikhani, Richardson, Richardson: "Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism." in: Biochimica et biophysica acta, Vol. 1833, Issue 6, pp. 1527-41, (2013) (PubMed).

Graham, Chua, Herbison, Olynyk, Trinder: "Liver iron transport." in: World journal of gastroenterology : WJG, Vol. 13, Issue 35, pp. 4725-36, (2007) (PubMed).

Ohgami, Campagna, McDonald, Fleming: "The Steap proteins are metalloreductases." in: Blood, Vol. 108, Issue 4, pp. 1388-94, (2006) (PubMed).

Ohgami, Campagna, Greer, Antiochos, McDonald, Chen, Sharp, Fujiwara, Barker, Fleming: "Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells." in: Nature genetics, Vol. 37, Issue 11, pp. 1264-9, (2005) (PubMed).

Synonyms and alternative names related to STEAP3

STEAP3 metalloreductase (STEAP3), STEAP3 metalloreductase (steap3), STEAP family member 3 (Steap3), STEAP3 metalloreductase (Steap3), 1010001D01Rik, AHMIO2, dudlin-2, pHyde, STEAP3, STMP3, Tsap6, TSAP6

Protein level used designations for STEAP3

  • STEAP family member 3
  • dudulin 2
  • metalloreductase STEAP3-like
  • dudulin-2
  • metalloreductase STEAP3
  • protein nm1054
  • six-transmembrane epithelial antigen of prostate 3
  • tumor suppressor-activated pathway protein 6
  • 1010001D01Rik
  • dudlin 2
  • hTSAP6
  • hpHyde
  • pHyde
  • six transmembrane prostate protein 3
  • tumor suppressor pHyde
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