STAT4 Products
(Signal Transducer and Activator of Transcription 4 (STAT4))
Categories
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].
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Featured STAT4 Categories
STAT4 Antibodies
High quality antibodies with extensive validation data.
STAT4 ELISA Kits
Reliable ELISA kits for a wide range of species.
STAT4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended STAT4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7443809
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN7262925
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IF, IHC (p)
Validations
- (9)
Cat. No.
ABIN563030
Quantity
100 μg
Datasheet
Datasheet
Recommended STAT4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validations
- (3)
- (5)
Cat. No.
ABIN1981841
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970219
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970218
Quantity
96 tests
Datasheet
Datasheet
Recommended STAT4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321598
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7417414
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3077563
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our STAT4 products
: "The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to radiation-induced lung fibrosis in mice." in: Molecular immunology, Vol. 80, pp. 33-40, (2017) (PubMed).: "Radiation-induced lung fibrosis in a tumor-bearing mouse model is associated with enhanced Type-2 immunity." in: Journal of radiation research, Vol. 57, Issue 2, pp. 133-41, (2017) (PubMed).
: "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation." in: EMBO molecular medicine, Vol. 4, Issue 10, pp. 1112-25, (2012) (PubMed).
: "Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 6, pp. 3839-47, (2009) (PubMed).
: "High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells." in: The Journal of experimental medicine, Vol. 204, Issue 10, pp. 2383-96, (2007) (PubMed).
: "Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).
: "PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21327-30, (2003) (PubMed).
: "Signaling through the JAK/STAT pathway, recent advances and future challenges." in: Gene, Vol. 285, Issue 1-2, pp. 1-24, (2002) (PubMed).
: "Activated STAT4 and a functional role for IL-12 in human Peyer's patches." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 300-7, (2002) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonyms and alternative names related to STAT4
signal transducer and activator of transcription 4 (STAT4), signal transducer and activator of transcription 4 (stat4), signal transducer and activator of transcription 4 (Stat4), SLEB11Protein level used designations for STAT4
- signal transducer and activator of transcription 4
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