ST14 Products
(Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))
Categories
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008].
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Featured ST14 Categories
ST14 Antibodies
High quality antibodies with extensive validation data.
ST14 ELISA Kits
Reliable ELISA kits for a wide range of species.
ST14 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ST14 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN669726
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6263143
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN652185
Quantity
400 μL
Datasheet
Datasheet
Recommended ST14 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959763
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883709
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386252
Quantity
96 tests
Datasheet
Datasheet
Recommended ST14 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321472
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321474
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505189
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ST14 products
: "Developmental mechanisms driving complex tooth shape in reptiles." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).: "Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis." in: PLoS genetics, Vol. 15, Issue 1, pp. e1007882, (2019) (PubMed).
: "Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis." in: The Journal of biological chemistry, Vol. 292, Issue 26, pp. 10801-10812, (2017) (PubMed).
: "Matriptase zymogen supports epithelial development, homeostasis and regeneration." in: BMC biology, Vol. 15, Issue 1, pp. 46, (2017) (PubMed).
: "Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin." in: The Journal of biological chemistry, Vol. 291, Issue 6, pp. 2577-82, (2016) (PubMed).
: "Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling." in: Nature communications, Vol. 6, pp. 6776, (2015) (PubMed).
: "Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors." in: Oncogene, Vol. 34, Issue 35, pp. 4664-72, (2015) (PubMed).
: "Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma." in: The Journal of investigative dermatology, Vol. 135, Issue 9, pp. 2283-91, (2015) (PubMed).
: "Regulation of feto-maternal barrier by matriptase- and PAR-2-mediated signaling is required for placental morphogenesis and mouse embryonic survival." in: PLoS genetics, Vol. 10, Issue 7, pp. e1004470, (2015) (PubMed).
: "Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium." in: Journal of virology, Vol. 87, Issue 8, pp. 4237-51, (2013) (PubMed).
Synonyms and alternative names related to ST14
suppression of tumorigenicity 14 (ST14), suppression of tumorigenicity 14 L homeolog (st14.L), suppression of tumorigenicity 14 (colon carcinoma) (St14), suppression of tumorigenicity 14 (St14), Epithin, HAI, hai, matriptase, mCAP3, MT-SP1, mt-sp1, MTSP1, mtsp1, PRSS14, prss14, Prss14, SNC19, snc19, st14, st14a, TADG15, tadg15, tmprss1, TMPRSS14, Tmprss14, XMT-SP1Protein level used designations for ST14
- membrane-type serine protease 1
- prostamin
- serine protease 14
- serine protease TADG-15
- suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
- suppressor of tumorigenicity 14 protein
- tumor associated differentially expressed gene 15 protein
- tumor-associated differentially-expressed gene 15 protein
- matriptase a
- suppression of tumorigenicity 14 (colon carcinoma) a
- suppressor of tumorigenicity 14 protein homolog
- suppressor of tumorigenicity protein 14
- matriptase/MT-SP1
- protease, serine, 14 (epithin)
- matriptase
- membrane-type serine protease
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