SRGN Products
(serglycin (SRGN))
Categories
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010].
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Featured SRGN Categories
SRGN Antibodies
High quality antibodies with extensive validation data.
SRGN ELISA Kits
Reliable ELISA kits for a wide range of species.
SRGN Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SRGN Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
- (2)
Cat. No.
ABIN519156
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7435199
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7168880
Quantity
100 μL
Datasheet
Datasheet
Recommended SRGN ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959372
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959373
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730770
Quantity
96 tests
Datasheet
Datasheet
Recommended SRGN Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321323
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321324
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396862
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SRGN products
: "SRGN, a new identified shear-stress-responsive gene in endothelial cells." in: Molecular and cellular biochemistry, Vol. 474, Issue 1-2, pp. 15-26, (2020) (PubMed).: "SRGN-TGFβ2 regulatory loop confers invasion and metastasis in triple-negative breast cancer." in: Oncogenesis, Vol. 6, Issue 7, pp. e360, (2017) (PubMed).
: "Serglycin in Quiescent and Proliferating Primary Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145584, (2015) (PubMed).
: "Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages." in: Biochimica et biophysica acta, Vol. 1840, Issue 6, pp. 1993-2003, (2014) (PubMed).
: "Serglycin secretion is part of the inflammatory response in activated primary human endothelial cells in vitro." in: Biochimica et biophysica acta, Vol. 1840, Issue 8, pp. 2498-505, (2014) (PubMed).
: "Serglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization." in: The Journal of biological chemistry, Vol. 289, Issue 9, pp. 5499-509, (2014) (PubMed).
: "Monocyte-to-macrophage differentiation: synthesis and secretion of a complex extracellular matrix." in: The Journal of biological chemistry, Vol. 287, Issue 17, pp. 14122-35, (2012) (PubMed).
: "Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis." in: Cancer research, Vol. 71, Issue 8, pp. 3162-72, (2011) (PubMed).
: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).
Synonyms and alternative names related to SRGN
serglycin (SRGN), serglycin (Srgn), Pgsg, PPG, PRG, Prg, PRG1, Prg1, SgcProtein level used designations for SRGN
- hematopoetic proteoglycan core peptide
- hematopoetic proteoglycan core protein
- hematopoietic proteoglycan core protein
- p.PG
- platelet proteoglycan core protein
- proteoglycan 1, secretory granule
- proteoglycan protein core for mast cell secretory granule
- secretory granule proteoglycan core peptide
- secretory granule proteoglycan core protein
- serglycin proteoglycan
- gp600
- mastocytoma proteoglycan core protein
- proteoglycan, secretory granule
- PG19 core protein
- chondroitin sulfate proteoglycan core protein
- cytolytic granule proteoglycan core protein
- proteoglycan 10K core protein
- proteoglycan peptide core protein
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