SRF Products
(Serum Response Factor (SRF))
Categories
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways\; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008].
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Featured SRF Categories
SRF Antibodies
High quality antibodies with extensive validation data.
SRF ELISA Kits
Reliable ELISA kits for a wide range of species.
SRF Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SRF Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro)
Validations
- (4)
Cat. No.
ABIN686017
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (4)
Cat. No.
ABIN6255577
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN520472
Quantity
100 μg
Datasheet
Datasheet
Recommended SRF ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970415
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380137
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5691922
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended SRF Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321311
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7415863
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2731854
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our SRF products
: "Neuroprotective effect of Ruminococcus albus on oxidatively stressed SH-SY5Y cells and animals." in: Scientific reports, Vol. 7, Issue 1, pp. 14520, (2018) (PubMed).: "Myc requires RhoA/SRF to reprogram glutamine metabolism." in: Small GTPases, pp. 1-9, (2016) (PubMed).
: "Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase." in: Cardiovascular research, Vol. 104, Issue 1, pp. 15-23, (2014) (PubMed).
: "The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 48, pp. 18836-48, (2013) (PubMed).
: "Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models." in: Oncogene, Vol. 31, Issue 16, pp. 2075-89, (2012) (PubMed).
: "Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice." in: The Journal of clinical investigation, Vol. 119, Issue 4, pp. 899-910, (2009) (PubMed).
: "Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin." in: Circulation research, Vol. 103, Issue 1, pp. 61-9, (2008) (PubMed).
: "Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts." in: American journal of physiology. Heart and circulatory physiology, Vol. 282, Issue 4, pp. H1521-33, (2002) (PubMed).
Synonyms and alternative names related to SRF
serum response factor (Srf), serum response factor (SRF), serum response factor L homeolog (srf.L), serum response factor a (srfa), AW049942, AW240594, MCM1, RGD1559787, srf, srf-A, srf1, SRFX, XSRFProtein level used designations for SRF
- serum response factor
- DreSrf1
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