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SREBF2 Products

(Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain. [provided by RefSeq, Jul 2008].

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Featured SREBF2 Categories

SREBF2 Antibodies

High quality antibodies with extensive validation data.

SREBF2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SREBF2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SREBF2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN3032752
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7170782
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN654630
Quantity 400 μL
Datasheet Datasheet

Recommended SREBF2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970433
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5592659
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1159829
Quantity 96 tests
Datasheet Datasheet

Recommended SREBF2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321309
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3114501
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135009
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SREBF2 products

Sharma, Gupta, Dahiya, Kumar, Vaiphei, Agnihotri: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).

Nguyen, Ishida, Shang, Shu, Bianchetti, Karpel-Massler, Siegelin: "Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors." in: Cancers, Vol. 11, Issue 6, (2019) (PubMed).

Lee, Kim, Kim, Park, Park: "Proteasome inhibition protects against diet-induced gallstone formation through modulation of cholesterol and bile acid homeostasis." in: International journal of molecular medicine, Vol. 41, Issue 3, pp. 1715-1723, (2018) (PubMed).

Mast, Lin, Anderson, Bjorkhem, Pikuleva: "Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1)." in: PLoS ONE, Vol. 12, Issue 10, pp. e0187168, (2017) (PubMed).

Ratovitski: "Delta Np63 alpha – Responsive microRNA Modulate the Expression of Metabolic Enzymes." in: Current pharmaceutical biotechnology, Vol. 16, Issue 9, pp. 832-50, (2015) (PubMed).

Daniëls, Smans, Royaux, Chypre, Swinnen, Zaidi: "Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment." in: PLoS ONE, Vol. 9, Issue 9, pp. e106913, (2014) (PubMed).

Takahashi, Kishimoto, Konishi, Fujita, Ito, Shimokado, Maruyama, Ishigami: "Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice." in: Biochimica et biophysica acta, Vol. 1840, Issue 7, pp. 2289-98, (2014) (PubMed).

Kondo, Masutomi, Noda, Ozawa, Takahashi, Handa, Maruyama, Shimizu, Ishigami: "Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis." in: FEBS open bio, Vol. 4, pp. 522-32, (2014) (PubMed).

Zhu, Jiang, Chehab: "FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2α at the CYP51 promoter." in: Journal of lipid research, Vol. 55, Issue 3, pp. 431-42, (2014) (PubMed).

Karanth, Tran, Kuberan, Schlegel: "Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice." in: Disease models & mechanisms, Vol. 6, Issue 6, pp. 1365-77, (2013) (PubMed).

Synonyms and alternative names related to SREBF2

sterol regulatory element binding transcription factor 2 (SREBF2), sterol regulatory element binding transcription factor 2 (srebf2), sterol regulatory element binding factor 2 (Srebf2), sterol regulatory element binding transcription factor 2 L homeolog (srebf2.L), sterol regulatory element binding transcription factor 2 (Srebf2), AI608257, bHLHd2, lop13, nuc, SREBF2, Srebf2_retired, SREBP-2, srebp2, SREBP2, SREBP2gc, zgc:158371

Protein level used designations for SREBF2

  • sterol regulatory element binding transcription factor 2
  • sterol regulatory element-binding protein 2-like
  • sterol regulatory element binding protein 2
  • SREBP-2
  • sterol regulatory element-binding protein 2
  • sterol regulatory element-binding transcription factor 2
  • class D basic helix-loop-helix protein 2
  • sterol regulatory element binding factor 2
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