SRD5A1 Products
(Steroid-5-alpha-Reductase, alpha Polypeptide 1 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 1) (SRD5A1))
Categories
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008].
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Featured SRD5A1 Categories
SRD5A1 Antibodies
High quality antibodies with extensive validation data.
SRD5A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SRD5A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SRD5A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN185346
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (1)
Cat. No.
ABIN520464
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7430156
Quantity
100 μL
Datasheet
Datasheet
Recommended SRD5A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970432
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962623
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959720
Quantity
96 tests
Datasheet
Datasheet
Recommended SRD5A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321300
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7386257
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7386254
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SRD5A1 products
: "Cerebellar Changes in Guinea Pig Offspring Following Suppression of Neurosteroid Synthesis During Late Gestation." in: Cerebellum (London, England), (2016) (PubMed).: "Increased Muscular 5α-Dihydrotestosterone in Response to Resistance Training Relates to Skeletal Muscle Mass and Glucose Metabolism in Type 2 Diabetic Rats." in: PLoS ONE, Vol. 11, Issue 11, pp. e0165689, (2016) (PubMed).
: "A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice." in: The Journal of steroid biochemistry and molecular biology, Vol. 150, pp. 35-45, (2015) (PubMed).
: "Changes in neuroactive steroid concentrations after preterm delivery in the Guinea pig." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 20, Issue 11, pp. 1365-75, (2013) (PubMed).
: "Repeated autologous bone marrow-derived mesenchymal stem cell injections improve radiation-induced proctitis in pigs." in: Stem cells translational medicine, Vol. 2, Issue 11, pp. 916-27, (2013) (PubMed).
: "5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis." in: Cancer cell international, Vol. 12, Issue 1, pp. 1, (2012) (PubMed).
: "DHEA administration activates local bioactive androgen metabolism in cancellous site of tibia of ovariectomized rats." in: Calcified tissue international, Vol. 89, Issue 2, pp. 105-10, (2011) (PubMed).
: "Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 33, pp. 13728-33, (2011) (PubMed).
: "Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development." in: The Journal of endocrinology, Vol. 208, Issue 3, pp. 301-9, (2011) (PubMed).
: "Insulin increases de novo steroidogenesis in prostate cancer cells." in: Cancer research, Vol. 71, Issue 17, pp. 5754-64, (2011) (PubMed).
Synonyms and alternative names related to SRD5A1
steroid 5 alpha-reductase 1 (SRD5A1), steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (srd5a1), 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Bm1_06570), 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (CC1G_14953), steroid 5 alpha-reductase 1 (Srd5a1), steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (SRD5A1), 0610031P22Rik, 4930435F02Rik, S5AR 1, Srd5a-1, zgc:153768Protein level used designations for SRD5A1
- steroid-5-alpha-reductase 1
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1
- SR type 1
- steroid 5-alpha-reductase 1
- type 1 5alpha-reductase
- 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1
- 5-alpha reductase
- steroid 5-alpha-reductase type I
- steroid 5 alpha-reductase 1
- prostatic steroid 5-alpha-reductase type I
- 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like
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