SQSTM1 Products
(Sequestosome 1 (SQSTM1))
Categories
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009].
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Featured SQSTM1 Categories
SQSTM1 Antibodies
High quality antibodies with extensive validation data.
SQSTM1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SQSTM1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SQSTM1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (22)
- (6)
Cat. No.
ABIN388979
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP, IHC (p), FACS, ICC, PLA
Validations
- (13)
- (23)
Cat. No.
ABIN2854836
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (5)
- (7)
Cat. No.
ABIN682153
Quantity
100 μL
Datasheet
Datasheet
Recommended SQSTM1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970104
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959370
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959371
Quantity
96 tests
Datasheet
Datasheet
Recommended SQSTM1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125031
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125032
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN666979
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SQSTM1 products
: "Antiviral Effects of ABMA and DABMA against Influenza Virus In Vitro and In Vivo via Regulating the Endolysosomal Pathway and Autophagy." in: , Vol. 23, Issue 7, (2022) (PubMed).: "GPA Peptide-Induced Nur77 Localization at Mitochondria Inhibits Inflammation and Oxidative Stress through Activating Autophagy in the Intestine." in: Oxidative medicine and cellular longevity, Vol. 2020, pp. 4964202, (2021) (PubMed).
: "Based on Activation of p62-Keap1-Nrf2 Pathway, Hesperidin Protects Arsenic-Trioxide-Induced Cardiotoxicity in Mice." in: Frontiers in pharmacology, Vol. 12, pp. 758670, (2021) (PubMed).
: "α-Solanine Causes Cellular Dysfunction of Human Trophoblast Cells via Apoptosis and Autophagy." in: Toxins, Vol. 13, Issue 1, (2021) (PubMed).
: "Activation of tumor-promoting pathways implicated in hepatocellular adenoma/carcinoma, a long-term complication of glycogen storage disease type Ia." in: Biochemical and biophysical research communications, Vol. 522, Issue 1, pp. 1-7, (2020) (PubMed).
: "Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes." in: Journal of Alzheimer's disease : JAD, Vol. 73, Issue 1, pp. 229-246, (2020) (PubMed).
: "ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 75, (2020) (PubMed).
: "Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy." in: Scientific reports, Vol. 10, Issue 1, pp. 8422, (2020) (PubMed).
: "Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment." in: EMBO molecular medicine, Vol. 12, Issue 5, pp. e10722, (2020) (PubMed).
: "Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy." in: EMBO reports, Vol. 21, Issue 7, pp. e48192, (2020) (PubMed).
Synonyms and alternative names related to SQSTM1
sequestosome 1 (SQSTM1), sequestosome 1 (sqstm1), sequestosome 1 (Sqstm1), sequestosome 1 L homeolog (sqstm1.L), A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, SQSTM1, sqstm1, STAP, zgc:85784, ZIP, ZIP3Protein level used designations for SQSTM1
- sequestosome 1
- sequestosome-1
- sequestosome-1-like
- sqstm1 protein
- EBI3-associated protein of 60 kDa
- EBI3-associated protein p60
- EBIAP
- oxidative stress induced like
- phosphotyrosine independent ligand for the Lck SH2 domain p62
- phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
- ubiquitin-binding protein p62
- STONE14
- oxidative stress induced
- PKC-zeta-interacting protein
- protein kinase C-zeta-interacting protein
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