SPTLC2 Products
(serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
Categories
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
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Featured SPTLC2 Categories
SPTLC2 Antibodies
High quality antibodies with extensive validation data.
SPTLC2 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPTLC2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPTLC2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN564104
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7168896
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
- (1)
Cat. No.
ABIN1881828
Quantity
400 μL
Datasheet
Datasheet
Recommended SPTLC2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959377
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232466
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658720
Quantity
96 tests
Datasheet
Datasheet
Recommended SPTLC2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321285
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321284
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408900
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SPTLC2 products
: "ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 12, pp. 3728-33, (2015) (PubMed).: "Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells." in: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 90-8, (2015) (PubMed).
: "Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).
: "Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 20, pp. 8186-91, (2009) (PubMed).
: "The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase." in: The Plant cell, Vol. 18, Issue 12, pp. 3576-93, (2007) (PubMed).
: "Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?" in: The Biochemical journal, Vol. 405, Issue 1, pp. 157-64, (2007) (PubMed).
: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).
: "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 7, pp. 3491-6, (2000) (PubMed).
Synonyms and alternative names related to SPTLC2
serine palmitoyltransferase long chain base subunit 2 (SPTLC2), serine palmitoyltransferase 2 (LOC100446763), serine palmitoyltransferase long chain base subunit 2 (sptlc2), serine palmitoyltransferase, long chain base subunit 2 S homeolog (sptlc2.S), serine palmitoyltransferase, long chain base subunit 2a (sptlc2a), serine palmitoyltransferase, long chain base subunit 2 (Sptlc2), serine palmitoyltransferase long chain base subunit 2 (Sptlc2), AI173915, hLCB2a, HSN1C, LCB2, LCB2A, LCB2a, mKIAA0526, NSAN1C, Pomt2, SPT2, sptlc2, SPTLC2, zgc:110661Protein level used designations for SPTLC2
- LCB 2
- SPT 2
- long chain base biosynthesis protein 2a
- serine palmitoyltransferase 2
- serine palmitoyltransferase, subunit II
- serine-palmitoyl-CoA transferase 2
- serine palmitoyltransferase, long chain base subunit 2
- serine palmitoyltransferase 2-like
- LCB2a
- long chain base biosynthesis protein 2
- protein-O-mannosyltransferase 2
- Long chain base biosynthesis protein 2
- Long chain base biosynthesis protein 2a
- Serine-palmitoyl-CoA transferase 2
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