SPTAN1 Products
(Spectrin alpha Chain, Brain (SPTAN1))
Categories
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
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Featured SPTAN1 Categories
SPTAN1 Antibodies
High quality antibodies with extensive validation data.
SPTAN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPTAN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPTAN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
Cat. No.
ABIN6148403
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7438451
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN7234066
Quantity
200 μL
Datasheet
Datasheet
Recommended SPTAN1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970386
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962314
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959657
Quantity
96 tests
Datasheet
Datasheet
Recommended SPTAN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401065
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7389866
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7400978
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SPTAN1 products
: "Blood-Based Brain and Global Biomarker Changes after Combined Hypoxemia and Hemorrhagic Shock in a Rat Model of Penetrating Ballistic-Like Brain Injury." in: Neurotrauma reports, Vol. 2, Issue 1, pp. 370-380, (2021) (PubMed).: "Activation of plasmacytoid dendritic cells by apoptotic particles - mechanism for the loss of immunological tolerance in Sjögren's syndrome." in: Clinical and experimental immunology, Vol. 191, Issue 3, pp. 301-310, (2019) (PubMed).
: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." in: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).
: "Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3527-36, (2002) (PubMed).
: "Characterization of human brain cDNA encoding the general isoform of beta-spectrin." in: The Journal of biological chemistry, Vol. 267, Issue 26, pp. 18715-22, (1992) (PubMed).
: "Generation of diversity in nonerythroid spectrins. Multiple polypeptides are predicted by sequence analysis of cDNAs encompassing the coding region of human nonerythroid alpha-spectrin." in: The Journal of biological chemistry, Vol. 265, Issue 8, pp. 4427-33, (1990) (PubMed).
Synonyms and alternative names related to SPTAN1
spectrin alpha, non-erythrocytic 1 (SPTAN1), spectrin alpha, non-erythrocytic 1 (sptan1), spectrin alpha, non-erythrocytic 1 (Sptan1), spectrin, alpha, non-erythrocytic 1 (Sptan1), 2610027H02Rik, A2a, EIEE5, im:7157190, IPF, NEAS, SPECA, Spna-2, Spna2, SPTA2, wu:fa20e05, wu:fb33g08, wu:fk32a10, zgc:112229Protein level used designations for SPTAN1
- alpha-fodrin
- spectrin alpha chain, brain
- spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
- cardiomyocyte alpha-spectrin
- sequence with a GC signal
- alpha2 spectrin
- Spectrin alpha chain, brain
- alpha-II spectrin
- alpha-spectrin 2, brain
- fodrin alpha chain
- spectrin alpha 2
- spectrin alpha chain, non-erythrocytic 1
- spectrin, non-erythroid alpha chain
- spectrin, non-erythroid alpha subunit
- a--fodrin
- alpha II spectrin
- alpha-spectrin 2
- brain alpha-spectrin
- inhibitory protein factor
- noerythroid alpha-spectrin 2
- nonerythroid alpha-spectrin 2
- alpha-spectrin
- nonerythroid alpha-spectrin
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