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SPTA1 Products

(Spectrin alpha 1, Erythrocytic (SPTA1))

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Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008].

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Featured SPTA1 Categories

SPTA1 Antibodies

High quality antibodies with extensive validation data.

SPTA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended SPTA1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (6)
Cat. No. ABIN6148401
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, Coat, StM
Validations
  • (6)
Cat. No. ABIN6940644
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7256054
Quantity 200 μL
Datasheet Datasheet

Recommended SPTA1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN5593058
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210223
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN6200069
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our SPTA1 products

Talhouarne, Gall: "7SL RNA in vertebrate red blood cells." in: RNA (New York, N.Y.), Vol. 24, Issue 7, pp. 908-914, (2018) (PubMed).

Ikeda, Dick, Weatherspoon, Gincel, Armbrust, Dalton, Stevanin, Dürr, Zühlke, Bürk, Clark, Brice, Rothstein, Schut, Day, Ranum: "Spectrin mutations cause spinocerebellar ataxia type 5." in: Nature genetics, Vol. 38, Issue 2, pp. 184-90, (2006) (PubMed).

Synonyms and alternative names related to SPTA1

spectrin, alpha, erythrocytic 1 (Spta1), spectrin alpha, erythrocytic 1 (Spta1), spectrin alpha, erythrocytic 1 (SPTA1), AF093576, AI451697, EL2, ha, HPP, HS3, ihj, nmf4, sph, SPH3, Spna-1, Spna1, SPTA

Protein level used designations for SPTA1

  • erythroid spectrin alpha
  • spectrin alpha chain, erythrocyte
  • alpha-spectrin 1, erythroid
  • erythroid alpha-spectrin
  • hemolytic anemia
  • neuroscience mutagenesis facility, 4
  • spectrin alpha 1
  • spectrin alpha chain, erythrocytic 1
  • spherocytosis
  • alpha-I spectrin
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