SPRY4 Products
(Sprouty RTK Signaling Antagonist 4 (SPRY4))
Categories
SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS\; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).[supplied by OMIM, Mar 2008].
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Featured SPRY4 Categories
SPRY4 Antibodies
High quality antibodies with extensive validation data.
SPRY4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPRY4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN652338
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6264444
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7251967
Quantity
200 μL
Datasheet
Datasheet
Recommended SPRY4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6232009
Quantity
96 tests
Datasheet
Datasheet
Recommended SPRY4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321265
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131926
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7424464
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SPRY4 products
: "Novel Function of Sprouty4 as a Regulator of Stemness and Differentiation of Embryonic Stem Cells." in: Development & reproduction, Vol. 20, Issue 2, pp. 171-7, (2016) (PubMed).: "Suppression of Sproutys has a therapeutic effect for a mouse model of ischemia by enhancing angiogenesis." in: PLoS ONE, Vol. 4, Issue 5, pp. e5467, (2009) (PubMed).
: "Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 287, Issue 1, pp. L52-9, (2004) (PubMed).
: "Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1." in: Nature cell biology, Vol. 5, Issue 5, pp. 427-32, (2003) (PubMed).
: "Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1." in: European journal of biochemistry / FEBS, Vol. 269, Issue 10, pp. 2546-56, (2002) (PubMed).
Synonyms and alternative names related to SPRY4
sprouty RTK signaling antagonist 4 (Spry4), sprouty RTK signaling antagonist 4 (SPRY4), sprouty (Drosophila) homolog 4 (spry4), sprouty homolog 4 (Drosophila) (Spry4), A030006O18Rik, HH17, LOC100218545, sprouty4, SPRY4Protein level used designations for SPRY4
- protein sprouty homolog 4
- sprouty-like protein 4
- sprouty homolog 4
- SPRY domain-containing protein 4
- spry-4
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