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SPRED1 Products

(Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))

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The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008].

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Featured SPRED1 Categories

SPRED1 Antibodies

High quality antibodies with extensive validation data.

SPRED1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPRED1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7170645
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS, IHC (p)
Validations
  • (2)
Cat. No. ABIN1959923
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN1539885
Quantity 400 μL
Datasheet Datasheet

Recommended SPRED1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131925
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7280801
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SPRED1 products

Baras, Gandhi, Munari, Faraj, Shultz, Marchionni, Schoenberg, Hahn, Hoque, Hoque, Berman, Bivalacqua, Netto: "Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Platinum Chemotherapy in Muscle Invasive Urothelial Carcinoma." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131245, (2015) (PubMed).

Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

Brems, Chmara, Sahbatou, Denayer, Taniguchi, Kato, Somers, Messiaen, De Schepper, Fryns, Cools, Marynen, Thomas, Yoshimura, Legius: "Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype." in: Nature genetics, Vol. 39, Issue 9, pp. 1120-6, (2007) (PubMed).

Yoshida, Hisamoto, Akiba, Koga, Nakamura, Tokunaga, Hanada, Kumemura, Maeyama, Harada, Ogata, Yano, Kojiro, Ueno, Yoshimura, Sata: "Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors." in: Oncogene, Vol. 25, Issue 45, pp. 6056-66, (2006) (PubMed).

Synonyms and alternative names related to SPRED1

sprouty-related, EVH1 domain containing 1 (spred1), sprouty related EVH1 domain containing 1 (SPRED1), sprouty related, EVH1 domain containing 1 (spred1), sprouty related, EVH1 domain containing 1 L homeolog (spred1.L), sprouty related EVH1 domain containing 1 (spred1), SPRED1 (Bm1_51610), sprouty protein with EVH-1 domain 1, related sequence (Spred1), sprouty-related, EVH1 domain containing 1 (Spred1), 5730461F13Rik, AL024345, AW047647, fb14c08, fj51c03, hSpred1, NFLS, spred-1, wu:fb14c08, wu:fj51c03, Xspred1, Xtspred1, zgc:85707

Protein level used designations for SPRED1

  • sprouty-related, EVH1 domain-containing protein 1
  • sprouty-related protein with EVH-1 domain 1
  • sprouty-related, EVH1 domain containing 1
  • spred-1
  • sprouty-related, EVH1 domain-containing protein 1-like
  • SPRED1
  • sprouty-related protein 1 with EVH-1 domain
  • suppressor of Ras/MAPK activation
  • sprouty protein with EVH-1 domain 1, related sequence
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