SPR Products
(Sepiapterin Reductase (SPR))
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This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008].
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SPR Antibodies
High quality antibodies with extensive validation data.
SPR ELISA Kits
Reliable ELISA kits for a wide range of species.
SPR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, IF, FACS, IHC (p)
Validations
- (14)
Cat. No.
ABIN1501111
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, FACS, IHC (p)
Validations
- (15)
Cat. No.
ABIN1501115
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IF, FACS
Validations
- (5)
Cat. No.
ABIN1501113
Quantity
100 μL
Datasheet
Datasheet
Recommended SPR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959363
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959364
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658710
Quantity
96 tests
Datasheet
Datasheet
Recommended SPR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN666753
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321239
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321241
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SPR products
: "Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line." in: Neuropharmacology, Vol. 99, pp. 79-88, (2015) (PubMed).: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).
: "Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation." in: Journal of molecular biology, Vol. 426, Issue 2, pp. 332-46, (2014) (PubMed).
: "Chitinase-like proteins are candidate biomarkers for sepsis-induced acute kidney injury." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 6, pp. M111.013094, (2012) (PubMed).
: "Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity." in: FEBS letters, Vol. 422, Issue 2, pp. 269-73, (1998) (PubMed).
: "Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 2, pp. 500-3, (1996) (PubMed).
: "The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells." in: Cell, Vol. 79, Issue 3, pp. 507-13, (1994) (PubMed).
Synonyms and alternative names related to SPR
sepiapterin reductase (SPR), sepiapterin reductase (Spr), Sepiapterin reductase (Sptr), sepiapterin reductase L homeolog (spr.L), sepiapterin reductase (sprE), sepiapterin reductase (CpipJ_CPIJ000511), sepiapterin reductase (sr), sepiapterin reductase (spr), sepiapterin reductase b (sprb), AA409688, CG12117, DDBDRAFT_0188686, DDBDRAFT_0191275, DDB_0188686, DDB_0191275, Dmel\\CG12117, ENSMUSG00000071345, Gm10328, SDR38C1, sptr, SR, xspr, zgc:194446Protein level used designations for SPR
- sepiapterin reductase
- short chain dehydrogenase/reductase family 38C, member 1
- CG12117-PA
- Sptr-PA
- 7,8-dihydrobiopterin:NADP+ oxidoreductase
- Sepiapterin reductase
- sepiapterin reductase b
- sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
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