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SPO11 Products

(SPO11 Meiotic Protein Covalently Bound To DSB Homolog (SPO11))

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Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008].

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Featured SPO11 Categories

SPO11 Antibodies

High quality antibodies with extensive validation data.

SPO11 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPO11 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN525320
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN525322
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7159201
Quantity 100 μg
Datasheet Datasheet

Recommended SPO11 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232461
Quantity 96 tests
Datasheet Datasheet

Recommended SPO11 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321209
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321211
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3077536
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SPO11 products

Suberbielle, Sanchez, Kravitz, Wang, Ho, Eilertson, Devidze, Kreitzer, Mucke: "Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β." in: Nature neuroscience, Vol. 16, Issue 5, pp. 613-21, (2013) (PubMed).

Synonyms and alternative names related to SPO11

Meiotic recombination protein spo-11 (spo-11), SPO11, initiator of meiotic double stranded breaks (SPO11), SPO11, initiator of meiotic double stranded breaks (Spo11), SPO11 meiotic protein covalently bound to DSB (spo11), SPO11 meiotic protein covalently bound to DSB (Spo11), AI449549, CT35, SPATA43, TOPVIA, zgc:77876

Protein level used designations for SPO11

  • SPO11 meiotic protein covalently bound to DSB homolog
  • cancer/testis antigen 35
  • meiotic recombination protein SPO11
  • spermatogenesis associated 43
  • sporulation protein, meiosis-specific, SPO11 homolog
  • sporulation protein, meiosis-specific, SPO11
  • sporulation protein, meiosis-specific, SPO11 homolog (S. cervisiae)
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