SPINT2 Products
(serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))
Categories
This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Featured SPINT2 Categories
SPINT2 Antibodies
High quality antibodies with extensive validation data.
SPINT2 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPINT2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPINT2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7436417
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7262667
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7157739
Quantity
100 μg
Datasheet
Datasheet
Recommended SPINT2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959383
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5510589
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5510588
Quantity
96 tests
Datasheet
Datasheet
Recommended SPINT2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN1098709
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321203
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7197930
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our SPINT2 products
: "Involvement of microglial cells in the antinociceptive effects of metamizol in a mouse model of neuropathic pain." in: Pharmacology, biochemistry, and behavior, Vol. 175, pp. 77-88, (2018) (PubMed).: "The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin." in: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22319-32, (2014) (PubMed).
: "Case of syndromic tufting enteropathy harbors SPINT2 mutation seen in congenital sodium diarrhea." in: Clinical dysmorphology, Vol. 19, Issue 1, pp. 48, (2009) (PubMed).
Synonyms and alternative names related to SPINT2
serine peptidase inhibitor, Kunitz type, 2 (Spint2), serine peptidase inhibitor, Kunitz type 2 (SPINT2), serine protease inhibitor, Kunitz type 2 (Spint2), AL024025, C76321, DIAR3, HAI-2, HAI2, Kop, Pb, PBProtein level used designations for SPINT2
- hepatocyte growth factor activator inhibitor type 2
- placental bikunin
- serine protease inhibitor, Kunitz type 2
- kunitz-type protease inhibitor 2
- serine protease inhibitor, Kunitz type, 2
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