SPINK1 Products
(serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
Categories
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008].
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Featured SPINK1 Categories
SPINK1 Antibodies
High quality antibodies with extensive validation data.
SPINK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPINK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPINK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IP
Validations
- (8)
- (5)
Cat. No.
ABIN562978
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (3)
Cat. No.
ABIN7436420
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7168925
Quantity
100 μg
Datasheet
Datasheet
Recommended SPINK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959380
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962684
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970111
Quantity
96 tests
Datasheet
Datasheet
Recommended SPINK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125036
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321179
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321181
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SPINK1 products
: "Surgical decompression of Wirsung duct reduces serum concentration of SPINK1 in patients with chronic pancreatitis." in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol. 18, Issue 3, pp. 275-279, (2018) (PubMed).: "Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers." in: Oncotarget, Vol. 6, Issue 34, pp. 35737-54, (2016) (PubMed).
: "Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial." in: Urologic oncology, Vol. 33, Issue 3, pp. 108.e5-108.e13, (2015) (PubMed).
: "Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India." in: The Prostate, Vol. 75, Issue 10, pp. 1051-62, (2015) (PubMed).
: "The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line." in: Tumour biology, (2015) (PubMed).
: "A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer." in: Tumour biology, Vol. 35, Issue 3, pp. 2759-67, (2014) (PubMed).
: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." in: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, (2014) (PubMed).
: "Serine protease inhibitor Kazal type 1 promotes epithelial-mesenchymal transition through EGFR signaling pathway in prostate cancer." in: The Prostate, Vol. 74, Issue 7, pp. 689-701, (2014) (PubMed).
: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." in: Urologic oncology, Vol. 31, Issue 8, pp. 1716-24, (2013) (PubMed).
: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, (2013) (PubMed).
Synonyms and alternative names related to SPINK1
serine peptidase inhibitor, Kazal type 1 (SPINK1), serine peptidase inhibitor, Kazal type 1 (Spink1), p12, PCTT, PSTI, Psti, SPINK1, Spink3, TATI, TCPProtein level used designations for SPINK1
- pancreatic secretory trypsin inhibitor
- serine protease inhibitor Kazal-type 1
- serine protease inhibitor, Kazal type 1
- tumor-associated trypsin inhibitor
- PSTI-II
- calcium transport inhibitor
- caltrin
- pancreatic secretory trypsin inhibitor II
- pancreatic secretory trypsin inhibitor type II (PSTI-II)
- serine peptidase inhibitor, Kazal type 3
- serine protease inhibitor Kazal-type 3
- serine protease inhibitor, Kazal type 3
- serine peptidase inhibitor, Kazal type 1
- prostatic secretory glycoprotein
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