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SPIB Products

(Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))

Categories

The protein encoded by this gene is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Featured SPIB Categories

SPIB Antibodies

High quality antibodies with extensive validation data.

SPIB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPIB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (2)
  • (7)
Cat. No. ABIN1098113
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
Cat. No. ABIN1881823
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN6736085
Quantity 100 μL
Datasheet Datasheet

Recommended SPIB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321172
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3131700
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3077379
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SPIB products

Sehgal, Donaldson, Pridans, Sauter, Hume, Mabbott: "The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche." in: Nature communications, Vol. 9, Issue 1, pp. 1272, (2018) (PubMed).

Donaldson, Sehgal, Rios, Williams, Mabbott: "Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility." in: PLoS pathogens, Vol. 12, Issue 12, pp. e1006075, (2017) (PubMed).

Sehgal, Kobayashi, Donaldson, Mabbott: "c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium." in: Immunobiology, Vol. 222, Issue 2, pp. 316-326, (2016) (PubMed).

Marshall, Dunham, Major: "Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity." in: The Journal of general virology, Vol. 91, Issue Pt 12, pp. 3042-52, (2010) (PubMed).

Liu, Invernizzi, Lu, Kosoy, Lu, Bianchi, Podda, Xu, Xie, Macciardi, Selmi, Lupoli, Shigeta, Ransom, Lleo, Lee, Mason, Myers, Peltekian, Ghent, Bernuzzi, Zuin, Rosina, Borghesio, Floreani et al.: "Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis...." in: Nature genetics, Vol. 42, Issue 8, pp. 658-60, (2010) (PubMed).

Nagasawa, Schmidlin, Hazekamp, Schotte, Blom: "Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B." in: European journal of immunology, Vol. 38, Issue 9, pp. 2389-400, (2008) (PubMed).

Schmidlin, Diehl, Nagasawa, Scheeren, Schotte, Uittenbogaart, Spits, Blom: "Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression." in: Blood, Vol. 112, Issue 5, pp. 1804-12, (2008) (PubMed).

Zhao, Yao, Xu, Lambeth, Smith, Kgosana, Wang, Nair: "A functional MicroRNA-155 ortholog encoded by the oncogenic Marek's disease virus." in: Journal of virology, Vol. 83, Issue 1, pp. 489-92, (2008) (PubMed).

Dontje, Schotte, Cupedo, Nagasawa, Scheeren, Gimeno, Spits, Blom: "Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B." in: Blood, Vol. 107, Issue 6, pp. 2446-52, (2006) (PubMed).

Geng, Vedeckis: "c-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter." in: The Journal of biological chemistry, Vol. 280, Issue 52, pp. 43264-71, (2005) (PubMed).

Synonyms and alternative names related to SPIB

Spi-B transcription factor L homeolog (spib.L), Spi-B transcription factor (SPIB), Spi-B transcription factor (Spi-1/PU.1 related) (Spib), Spi-B transcription factor (Spib), B42b-like, spi-b, SPI-B, Spi-B, spib, spiba

Protein level used designations for SPIB

  • Spi-B transcription factor (Spi-1/PU.1 related) a
  • transcription factor Spi-B
  • Ets transcription factor Spi-B
  • Spi-1/PU.1 related
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