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SPG7 Products

(Spastic Paraplegia 7 (SPG7))

Categories

This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq, Jul 2008].

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Featured SPG7 Categories

SPG7 Antibodies

High quality antibodies with extensive validation data.

SPG7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPG7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF, FACS
Validations
  • (5)
Cat. No. ABIN1491371
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (3)
Cat. No. ABIN1491369
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN656408
Quantity 400 μL
Datasheet Datasheet

Recommended SPG7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321156
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321154
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3119231
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SPG7 products

Cesnekova, Rodinova, Hansikova, Zeman, Stiburek: "Loss of Mitochondrial AAA Proteases AFG3L2 and YME1L Impairs Mitochondrial Structure and Respiratory Chain Biogenesis." in: International journal of molecular sciences, Vol. 19, Issue 12, (2019) (PubMed).

Kim, Lee, Cho, Kim, Won: "Dopamine D3 receptor-modulated neuroprotective effects of lisuride." in: Neuropharmacology, Vol. 117, pp. 14-20, (2017) (PubMed).

Choi, Yun, Lee, Park, Park, Kim: "Proteomic Analysis of a Rat Cerebral Ischemic Injury Model after Human Cerebral Endothelial Cell Transplantation." in: Journal of Korean Neurosurgical Society, Vol. 59, Issue 6, pp. 544-550, (2016) (PubMed).

Synonyms and alternative names related to SPG7

SPG7, paraplegin matrix AAA peptidase subunit (SPG7), SPG7, paraplegin matrix AAA peptidase subunit (Spg7), AI452278, AU015315, CAR, CMAR, Cmar, PGN, SPG5C

Protein level used designations for SPG7

  • paraplegin
  • spastic paraplegia 7
  • spastic paraplegia 7 homolog
  • spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)
  • cell adhesion regulator
  • cell matrix adhesion regulator
  • spastic paraplegia 7 protein
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