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Spexin Products

(Spexin (SPX))

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Plays a role as a central modulator of cardiovascular and renal function and nociception. Plays also a role in energy metabolism and storage. Inhibits adrenocortical cell proliferation with minor stimulation on corticosteroid release (By similarity). {ECO:0000250}. Spexin-1: Intracerebroventricular administration of the peptide induces an increase in arterial blood pressure, a decrease in both heart rate and renal excretion and delayed natriuresis. Intraventricular administration of the peptide induces antinociceptive activity. Also induces contraction of muscarinic- like stomach smooth muscles. Acts as a ligand for galanin receptors GALR2 and GALR3 (By similarity). Intraperitoneal administration of the peptide induces a reduction in food consumption and body weight. Inhibits long chain fatty acid uptake into adipocytes (PubMed:24550067). {ECO:0000250, ECO:0000269|PubMed:24550067}. Spexin-2: Intracerebroventricular administration of the peptide induces a decrease in heart rate, but no change in arterial pressure, and an increase in urine flow rate. Intraventricular administration of the peptide induces antinociceptive activity (By similarity). {ECO:0000250}.

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Recommended Spexin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN797242
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN797244
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN797243
Quantity 100 μL
Datasheet Datasheet

Recommended Spexin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6962709
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969968
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our Spexin products

Guler, Demir: "Decreased levels of spexin are associated with hormonal and metabolic disturbance in subjects with polycystic ovary syndrome." in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, pp. 1-6, (2020) (PubMed).

Ceylan, Saygın, Özel Türkcü: "Assessment of acute aerobic exercise in the morning versus evening on asprosin, spexin, lipocalin-2, and insulin level in overweight/obese versus normal weight adult men." in: Chronobiology international, Vol. 37, Issue 8, pp. 1252-1268, (2020) (PubMed).

Synonyms and alternative names related to Spexin

spexin hormone (SPX), spexin hormone (Spx), Npq, Spx

Protein level used designations for Spexin

  • NPQ
  • neuropeptide Q
  • spexin
  • LRRGT00060
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