SPARC Products
(Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
Categories
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. [provided by RefSeq, Dec 2011].
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Featured SPARC Categories
SPARC Antibodies
High quality antibodies with extensive validation data.
SPARC ELISA Kits
Reliable ELISA kits for a wide range of species.
SPARC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPARC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
- (13)
Cat. No.
ABIN738141
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN562974
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS
Validations
- (7)
Cat. No.
ABIN3032525
Quantity
0.4 mL
Datasheet
Datasheet
Recommended SPARC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6959305
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6962272
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959306
Quantity
96 tests
Datasheet
Datasheet
Recommended SPARC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275640
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275639
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275641
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SPARC products
: "Interstitial changes after reperfused myocardial infarction in swine: morphometric and genetic analysis." in: BMC veterinary research, Vol. 16, Issue 1, pp. 262, (2021) (PubMed).: "Kaempferol-zinc(II) complex synthesis and evaluation of bone formation using zebrafish model." in: Life sciences, Vol. 256, pp. 117993, (2020) (PubMed).
: "Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells." in: PLoS ONE, Vol. 13, Issue 10, pp. e0206756, (2019) (PubMed).
: "Extracellular SPARC increases cardiomyocyte contraction during health and disease." in: PLoS ONE, Vol. 14, Issue 4, pp. e0209534, (2019) (PubMed).
: "Potential Prediction of Acute Biliary Pancreatitis Outcome on Admission." in: Pancreas, Vol. 47, Issue 4, pp. 454-458, (2018) (PubMed).
: "Implication of SPARC in the modulation of the extracellular matrix and mitochondrial function in muscle cells." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192714, (2018) (PubMed).
: "SPARC and GluA1-Containing AMPA Receptors Promote Neuronal Health Following CNS Injury." in: Frontiers in cellular neuroscience, Vol. 12, pp. 22, (2018) (PubMed).
: "Surface modification of polymer nanoparticles with native albumin for enhancing drug delivery to solid tumors." in: Biomaterials, Vol. 180, pp. 206-224, (2018) (PubMed).
: "Suboptimal Level of Bone-Forming Cells in Advanced Cirrhosis are Associated with Hepatic Osteodystrophy." in: Hepatology communications, Vol. 2, Issue 9, pp. 1095-1110, (2018) (PubMed).
: "Association of Bone Metabolic Markers With Diabetic Retinopathy and Diabetic Macular Edema in Elderly Chinese Individuals With Type 2 Diabetes Mellitus." in: The American journal of the medical sciences, Vol. 354, Issue 4, pp. 355-361, (2017) (PubMed).
Synonyms and alternative names related to SPARC
secreted protein acidic and cysteine rich (SPARC), secreted acidic cysteine rich glycoprotein (Sparc), secreted protein acidic and cysteine rich (Sparc), secreted protein, acidic, cysteine-rich (osteonectin) (sparc), secreted protein, acidic, cysteine-rich (osteonectin) L homeolog (sparc.L), secreted protein, acidic, cysteine-rich (osteonectin) (SPARC), secreted protein, acidic, cysteine-rich (osteonectin) S homeolog (sparc.S), AA517111, BM-40, hm:zeh0062, ON, SPARC, sparcProtein level used designations for SPARC
- BM-40
- basement-membrane protein 40
- cysteine-rich protein
- osteonectin
- secreted protein acidic and rich in cysteine
- ON
- SPARC
- Secreted acidic cystein-rich glycoprotein (osteonectin)
- secreted acidic cysteine rich glycoprotein
- osn
- secreted protein, acidic, cysteine-rich (osteonectin) S homeolog
- secreted protein, acidic, cysteine-rich (osteonectin)
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