SPAG8 Products
(Sperm Associated Antigen 8 (SPAG8))
Categories
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq, Jul 2012].
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Featured SPAG8 Categories
SPAG8 Antibodies
High quality antibodies with extensive validation data.
SPAG8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SPAG8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN525626
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN525625
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7170484
Quantity
100 μg
Datasheet
Datasheet
Recommended SPAG8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6211902
Quantity
96 tests
Datasheet
Datasheet
Recommended SPAG8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321065
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321064
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135120
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SPAG8 products
: "The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population." in: European journal of epidemiology, Vol. 23, Issue 1, pp. 23-7, (2008) (PubMed).Synonyms and alternative names related to SPAG8
sperm associated antigen 8 (SPAG8), sperm associated antigen 8 (Spag8), BS-84, HSD-1, hSMP-1, MH-SPAG8, SMP1, SPAG3Protein level used designations for SPAG8
- sperm membrane protein 1
- sperm membrane protein BS-84
- sperm-associated antigen 8
- sperm associated antigen 8-like protein
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