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SPAG1 Products

(Sperm Associated Antigen 1 (SPAG1))
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein. [provided by RefSeq, Jul 2008].

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Featured SPAG1 Categories

SPAG1 Antibodies

High quality antibodies with extensive validation data.

SPAG1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SPAG1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPAG1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN5014338
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7192612
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN651886
Quantity 400 μL
Datasheet Datasheet

Recommended SPAG1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970388
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6211516
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1159358
Quantity 96 tests
Datasheet Datasheet

Recommended SPAG1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321052
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417930
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3095660
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to SPAG1

sperm associated antigen 1 (SPAG1), sperm associated antigen 1a (spag1a), sperm associated antigen 1 (CpipJ_CPIJ006297), sperm associated antigen 1 (spag1), sperm associated antigen 1 (Spag1), cb1089, hsd-3.8, HSD-3.8, MGC162178, sp75, SP75, tpis, TPIS, wu:fj78g10

Protein level used designations for SPAG1

  • sperm associated antigen 1
  • sperm-associated antigen 1
  • TPR-containing protein involved in spermatogenesis
  • infertility-related sperm protein Spag-1
  • tetratricopeptide repeat-containing protein
  • HSD-3.8
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