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SP110 Products

(SP110 Nuclear Body Protein (SP110))

Categories

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008].

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Featured SP110 Categories

SP110 Antibodies

High quality antibodies with extensive validation data.

SP110 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SP110 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IP, RNAi
Validations
  • (7)
Cat. No. ABIN561432
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN516830
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (4)
Cat. No. ABIN948008
Quantity 50 μg
Datasheet Datasheet

Recommended SP110 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207622
Quantity 96 tests
Datasheet Datasheet

Recommended SP110 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321023
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3077253
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3125318
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SP110 products

de la Fuente, Manzano-Roman, Blouin, Naranjo, Kocan: "Sp110 transcription is induced and required by Anaplasma phagocytophilum for infection of human promyelocytic cells." in: BMC infectious diseases, Vol. 7, pp. 110, (2007) (PubMed).

Tosh, Campbell, Fielding, Sillah, Bah, Gustafson, Manneh, Lisse, Sirugo, Bennett, Aaby, McAdam, Bah-Sow, Lienhardt, Kramnik, Hill: "Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 27, pp. 10364-8, (2006) (PubMed).

Pan, Yan, Rojas, Shebzukhov, Zhou, Kobzik, Higgins, Daly, Bloom, Kramnik: "Ipr1 gene mediates innate immunity to tuberculosis." in: Nature, Vol. 434, Issue 7034, pp. 767-72, (2005) (PubMed).

Bloch, Nakajima, Gulick, Chiche, Orth, de La Monte, Bloch: "Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator." in: Molecular and cellular biology, Vol. 20, Issue 16, pp. 6138-46, (2000) (PubMed).

Synonyms and alternative names related to SP110

SP110 nuclear body protein (SP110), Sp110 nuclear body protein (Sp110), SP110 nuclear body protein (Sp110), 52kDa, 5031415C07Rik, 5830484A20Rik, ENSMUSG00000075603, IFI41, IFI75, Ifi75, IPR1, Ipr1, SP110, VODI

Protein level used designations for SP110

  • SP110 nuclear body protein
  • sp110 nuclear body protein-like
  • interferon-induced protein 41, 30kD
  • interferon-induced protein 41/75
  • interferon-induced protein 75, 52kD
  • phosphoprotein 41
  • phosphoprotein 75
  • sp110 nuclear body protein
  • speckled 110 kDa
  • transcriptional coactivator Sp110
  • intracellular pathogen resistance 1
  • intracellular pathogen resistance protein 1
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