SP100 Products
(SP100 Nuclear Antigen (SP100))
Categories
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene\; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011].
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Featured SP100 Categories
SP100 Antibodies
High quality antibodies with extensive validation data.
SP100 ELISA Kits
Reliable ELISA kits for a wide range of species.
SP100 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SP100 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7442741
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (1)
- (4)
Cat. No.
ABIN562971
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (3)
Cat. No.
ABIN948494
Quantity
50 μg
Datasheet
Datasheet
Recommended SP100 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN511609
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rabbit
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN775695
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN777660
Quantity
96 tests
Datasheet
Datasheet
Recommended SP100 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321019
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321021
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2131910
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SP100 products
: "The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection." in: PLoS ONE, Vol. 12, Issue 1, pp. e0169648, (2017) (PubMed).: "Quantification of the host response proteome after herpes simplex virus type 1 infection." in: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, (2015) (PubMed).
: "Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1." in: Viruses, Vol. 7, Issue 6, pp. 2884-907, (2015) (PubMed).
: "Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity." in: PLoS pathogens, Vol. 10, Issue 1, pp. e1003863, (2014) (PubMed).
: "Sp100 provides intrinsic immunity against human papillomavirus infection." in: mBio, Vol. 4, Issue 6, pp. e00845-13, (2013) (PubMed).
: "Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100." in: The Journal of general virology, Vol. 92, Issue Pt 7, pp. 1532-8, (2011) (PubMed).
: "Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle." in: Journal of virology, Vol. 85, Issue 18, pp. 9447-58, (2011) (PubMed).
Synonyms and alternative names related to SP100
SP100 nuclear antigen (SP100), nuclear antigen Sp100 (Sp100), SP100 nuclear antigen (Sp100), nuclear autoantigen Sp-100 (LOC101120993), A430075G10Rik, lysp100b, SP100, SP140Protein level used designations for SP100
- SP100 nuclear antigen
- nuclear autoantigen Sp-100
- nuclear autoantigen Sp-100-like
- nuclear dot-associated Sp100 protein
- speckled 100 kDa
- SP100-HMG nuclear autoantigen
- nuclear antigen Sp100
- Nuclear autoantigen Sp-100
- SP140 nuclear body protein
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