SOX4 Products
(SRY (Sex Determining Region Y)-Box 4 (SOX4))
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This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008].
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Featured SOX4 Categories
SOX4 Antibodies
High quality antibodies with extensive validation data.
SOX4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SOX4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
- (5)
Cat. No.
ABIN1387237
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN388786
Quantity
400 μL
Datasheet
Datasheet
Recommended SOX4 Proteins
Latest Publications for our SOX4 products
: "The SOX4/miR-17-92/RB1 Axis Promotes Prostate Cancer Progression." in: Neoplasia (New York, N.Y.), Vol. 21, Issue 8, pp. 765-776, (2019) (PubMed).: "Down-regulated SOX4 expression suppresses cell proliferation, metastasis and induces apoptosis in Xuanwei female lung cancer patients." in: Journal of cellular biochemistry, Vol. 116, Issue 6, pp. 1007-18, (2015) (PubMed).
: "SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells." in: Molecular cancer, Vol. 14, pp. 24, (2015) (PubMed).
: "SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 30, Issue 9, pp. 1560-71, (2015) (PubMed).
: "miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes." in: Journal of cancer research and clinical oncology, Vol. 140, Issue 8, pp. 1295-304, (2014) (PubMed).
: "A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness." in: PLoS ONE, Vol. 8, Issue 1, pp. e53328, (2013) (PubMed).
: "The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells." in: Development (Cambridge, England), Vol. 140, Issue 4, pp. 740-50, (2013) (PubMed).
: "The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer." in: Human molecular genetics, Vol. 18, Issue 7, pp. 1343-52, (2009) (PubMed).
: "Effects of TGFbeta1 on gene expression in the HP75 human pituitary tumor cell line identified by gene expression profiling." in: Endocrine, Vol. 33, Issue 1, pp. 62-76, (2008) (PubMed).
Synonyms and alternative names related to SOX4
SRY-box 4 (SOX4), SRY box 4 (Sox4), SRY (sex determining region Y)-box 4 (Sox4), SRY (sex determining region Y)-box 4a (sox4a), AA682046, EVI16, Sox-4, sox4, wu:fb82f08, wu:fq41g10, zgc:65850, zgc:77392Protein level used designations for SOX4
- SRY-box containing protein 4
- transcription factor SOX-4
- SRY-related HMG-box gene 4
- ecotropic viral integration site 16
- SRY-box containing gene 4
- SRY (sex determining region Y)-box 4
- SRY (sex determining region Y)-box 4a
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