SOX17B.2 Proteins
(SRY (Sex Determining Region Y)-Box 17 Beta, Gene 2 (SOX17B.2))
Transcription activator. Doesn't appear to bind to the consensus 5'-AACAAT-3' DNA binding site, but binds 5'-ATTGTT-3'. All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in function. In addition, the sox17 proteins have distinct but overlapping roles in later gut development. Acts downstream of vegt-signaling in endoderm differentiation to induce a range of endodermal genes both directly and indirectly. Also represses wnt- responsive genes to inhibit wnt/beta-catenin-mediated signaling (By similarity).
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Recommended SOX17B.2 Proteins
Synonyms and alternative names related to SOX17B.2
SRY (sex determining region Y)-box 17 beta, gene 2 L homeolog (sox17b.2.L), sox17, sox17b.3, tSox17beta, Xsox17Protein level used designations for SOX17B.2
- transcription factor Sox-17-beta.3
- SRY (sex determining region Y)-box 17-beta.3
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