Sortilin 1 Products
(Sortilin 1 (SORT1))
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This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes\; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p\; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq, Jul 2008].
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Featured Sortilin 1 Categories
Sortilin 1 Antibodies
High quality antibodies with extensive validation data.
Sortilin 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Sortilin 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Sortilin 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (5)
Cat. No.
ABIN562759
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN6148281
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7170335
Quantity
100 μg
Datasheet
Datasheet
Recommended Sortilin 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970373
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959642
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959643
Quantity
96 tests
Datasheet
Datasheet
Recommended Sortilin 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125176
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125175
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320971
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Sortilin 1 products
: "proBDNF is modified by advanced glycation end products in Alzheimer's disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing." in: Molecular brain, Vol. 11, Issue 1, pp. 68, (2019) (PubMed).: "Circulating sortilin level as a potential biomarker for coronary atherosclerosis and diabetes mellitus." in: Cardiovascular diabetology, Vol. 16, Issue 1, pp. 92, (2018) (PubMed).
: "Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques." in: Alzheimer's research & therapy, Vol. 10, Issue 1, pp. 40, (2018) (PubMed).
: "Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin." in: Scientific reports, Vol. 8, Issue 1, pp. 9006, (2018) (PubMed).
: "Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture." in: Scientific reports, Vol. 8, Issue 1, pp. 804, (2018) (PubMed).
: "Sortilin regulates sorting and secretion of Sonic hedgehog." in: Journal of cell science, Vol. 129, Issue 20, pp. 3832-3844, (2016) (PubMed).
: "SORT1 Mutation Resulting in Sortilin Deficiency and p75(NTR) Upregulation in a Family With Essential Tremor." in: ASN neuro, Vol. 7, Issue 4, (2015) (PubMed).
: "Production and Characterization of a Novel Monoclonal Antibody Against Human Sortilin." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 34, Issue 6, pp. 390-5, (2015) (PubMed).
: "Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other." in: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18609-20, (2015) (PubMed).
: "Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency." in: Human molecular genetics, Vol. 23, Issue 6, pp. 1467-78, (2014) (PubMed).
Synonyms and alternative names related to Sortilin 1
sortilin 1 (SORT1), sortilin (TP01_0016), sortilin (BBOV_I002730), sortilin 1 S homeolog (sort1.S), sortilin 1 (Sort1), sortilin 1a (sort1a), 19.m02079, 2900053A11Rik, AI852375, gp95, Gp95, ldlcq6, LDLCQ6, NT3, Nt3, Ntr3, Nts3, Ntsr3, SORT1, sort1, sortilin, zgc:85953Protein level used designations for Sortilin 1
- sortilin 1
- sortilin
- sortilin-like
- 100 kDa NT receptor
- NTR3
- glycoprotein 95
- neurotensin receptor 3
- mNTR3
- glycoprotein 110
- gp110
Did you look for something else?
- SORL1
- SORD
- SORCS3
- SORCS2
- SORCS1
- SORCS1
- Sorbs2
- SORBS1
- Sonic Hedgehog
- SON
- Somatotropin-2
- Somatostatin
- Somatolactin
- Solute Carrier Organic Anion Transporter Family, Member 3A1
- Solute Carrier Organic Anion Transporter Family, Member 1a4
- Solute Carrier Family 7 (Anionic Amino Acid Transporter), Member 13
- Solute Carrier Family 6 (Neutral Amino Acid Transporter), Member 19
- Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4
- Solute Carrier Family 52 (Riboflavin Transporter), Member 3
- Solute Carrier Family 5 (Sodium/inositol Cotransporter), Member 11
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