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(SON DNA Binding Protein (SON))

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The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq, Jul 2008].

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Featured SON Categories

SON Antibodies

High quality antibodies with extensive validation data.

SON ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended SON Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
  • (2)
Cat. No. ABIN768615
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7270496
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC, ICC, IF
Validations
Cat. No. ABIN7094603
Quantity 100 μL
Datasheet Datasheet

Recommended SON ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1152515
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1152516
Quantity 96 tests
Datasheet Datasheet

Recommended SON Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1784957
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SON products

Lu, Ang, Zhuang: "Spatially resolved epigenomic profiling of single cells in complex tissues." in: Cell, Vol. 185, Issue 23, pp. 4448-4464.e17, (2022) (PubMed).

Ammon, Mishra, Kowalska, Popowicz, Holak, Jentsch: "The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells." in: Journal of molecular cell biology, Vol. 6, Issue 4, pp. 312-23, (2014) (PubMed).

Uhlén, Oksvold, Älgenäs, Hamsten, Fagerberg, Klevebring, Lundberg, Odeberg, Pontén, Kondo, Sivertsson: "Antibody-based protein profiling of the human chromosome 21." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. M111.013458, (2012) (PubMed).

Fuchs, Pau, Kranz, Sklyar, Budjan, Steinbrink, Horn, Pedal, Huber, Boutros: "Clustering phenotype populations by genome-wide RNAi and multiparametric imaging." in: Molecular systems biology, Vol. 6, pp. 370, (2010) (PubMed).

Synonyms and alternative names related to SON

SON DNA binding protein (SON), SON DNA binding protein (EHI_129760), Son DNA binding protein (Son), 2900011L12Rik, AA409051, AU067731, BASS1, C21orf50, C81487, DBP-5, DKFZp469P034, mKIAA1019, NREBP, nrebp, SON3

Protein level used designations for SON

  • SON DNA binding protein
  • SON DNA-binding protein
  • protein SON
  • SON DNA binding protein, isoform f
  • Bax antagonist selected in Saccharomyces 1
  • NRE-binding protein
  • negative regulatory element-binding protein
  • Son cell proliferation protein
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