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(SON DNA Binding Protein (SON))
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The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq, Jul 2008].
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Featured SON Categories
SON Antibodies
High quality antibodies with extensive validation data.
SON ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended SON Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
- (2)
Cat. No.
ABIN768615
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7270496
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC, ICC, IF
Validations
Cat. No.
ABIN7094603
Quantity
100 μL
Datasheet
Datasheet
Recommended SON ELISA Kits
Recommended SON Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1784957
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SON products
: "Spatially resolved epigenomic profiling of single cells in complex tissues." in: Cell, Vol. 185, Issue 23, pp. 4448-4464.e17, (2022) (PubMed).: "The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells." in: Journal of molecular cell biology, Vol. 6, Issue 4, pp. 312-23, (2014) (PubMed).
: "Antibody-based protein profiling of the human chromosome 21." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. M111.013458, (2012) (PubMed).
: "Clustering phenotype populations by genome-wide RNAi and multiparametric imaging." in: Molecular systems biology, Vol. 6, pp. 370, (2010) (PubMed).
Synonyms and alternative names related to SON
SON DNA binding protein (SON), SON DNA binding protein (EHI_129760), Son DNA binding protein (Son), 2900011L12Rik, AA409051, AU067731, BASS1, C21orf50, C81487, DBP-5, DKFZp469P034, mKIAA1019, NREBP, nrebp, SON3Protein level used designations for SON
- SON DNA binding protein
- SON DNA-binding protein
- protein SON
- SON DNA binding protein, isoform f
- Bax antagonist selected in Saccharomyces 1
- NRE-binding protein
- negative regulatory element-binding protein
- Son cell proliferation protein
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