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Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 Products

(Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

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This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008].

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Featured Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 Categories

Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 Antibodies

High quality antibodies with extensive validation data.

Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (5)
Cat. No. ABIN7435223
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC, FACS, LCI, IF
Validations
  • (5)
Cat. No. ABIN7043745
Quantity 25 μL
Datasheet Datasheet
Reactivity Chicken, Human, Mouse, Rat
Application WB, ELISA, IF (p), IHC (p)
Validations
  • (6)
  • (2)
Cat. No. ABIN735983
Quantity 100 μL
Datasheet Datasheet

Recommended Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6959618
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6959619
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959620
Quantity 96 tests
Datasheet Datasheet

Recommended Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320509
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320511
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2732177
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 products

Li, Wang, Huang, Li, Zhang: "Effects of regulating gut microbiota on the serotonin metabolism in the chronic unpredictable mild stress rat model." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 31, Issue 10, pp. e13677, (2020) (PubMed).

Llobet, Vallvé, Tirado, Vilalta, Murillo, Cuevas, Román, Carrasco, Oliver, Mateo, Fontcuberta, Souto: "VAMP8 and serotonin transporter levels are associated with venous thrombosis risk in a Spanish female population. Results from the RETROVE Project." in: Thrombosis research, Vol. 181, pp. 99-105, (2020) (PubMed).

Yousef, Khalil, Abdou et al.: "Neuro- and nephroprotective effect of grape seed proanthocyanidin extract against carboplatin and thalidomide through modulation of inflammation, tumor suppressor protein p53, neurotransmitters, ..." in: Toxicology reports, Vol. 5, pp. 568-578, (2018) (PubMed).

Minakuchi, Sogawa, Miki, Hara, Maekawa, Sogawa, Kitayama, Matsuka, Clark, Kuboki: "Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects." in: Sleep & breathing = Schlaf & Atmung, Vol. 20, Issue 1, pp. 271-6, (2016) (PubMed).

Yu, Huang, Zhang, Ye, Chi, Zou, Lv, Zheng: "Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis." in: World journal of gastroenterology, Vol. 22, Issue 12, pp. 3451-9, (2016) (PubMed).

Wang, Gu, Liu, Bai, Wang: "Fluoxetine protects against methamphetamine‑induced lung inflammation by suppressing oxidative stress through the SERT/p38 MAPK/Nrf2 pathway in rats." in: Molecular medicine reports, Vol. 15, Issue 2, pp. 673-680, (2016) (PubMed).

Popova, Forsblad, Hashemian, Jacobsson: "Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived from Mouse P19 Embryonal Carcinoma Cells." in: PLoS ONE, Vol. 11, Issue 11, pp. e0166750, (2016) (PubMed).

Savy, Fitchett, McQuade, Gartside, Morris, Blain, Judge: "Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour." in: Neurotoxicology, Vol. 50, pp. 149-56, (2015) (PubMed).

Bielas, Arck, Bruenahl, Walitza, Grünblatt: "Prenatal stress increases the striatal and hippocampal expression of correlating c-FOS and serotonin transporters in murine offspring." in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, Vol. 38, pp. 30-5, (2015) (PubMed).

Frey, Popp, Post, Langer, Lehmann, Hofmann, Sirén, Hommers, Schmitt, Strekalova, Ertl, Lesch, Frantz: "Experimental heart failure causes depression-like behavior together with differential regulation of inflammatory and structural genes in the brain." in: Frontiers in behavioral neuroscience, Vol. 8, pp. 376, (2014) (PubMed).

Synonyms and alternative names related to Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4

solute carrier family 6 member 4 (SLC6A4), solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (Slc6a4), solute carrier family 6 member 4 (Slc6a4), Serotonin transporter (SerT), huntingtin (LOC100540532), solute carrier family 6 member 4 (slc6a4), solute carrier family 6 (neurotransmitter transporter), member 4b (slc6a4b), solute carrier family 6 (neurotransmitter transporter), member 4a (slc6a4a), 5-HTT, 5-HTTLPR, 5HTT, AI323329, CG4545, Dmel\\CG4545, DmSERT, DmSerT, dSERT, dSerT, dSert, dsert, dSERT1, hSERT, HTT, Htt, OCD1, SERT, Sert, SERT1, SLC6A4

Protein level used designations for Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4

  • 5-hydroxytryptamine (serotonin) transporter
  • 5-hydroxytryptamine transporter
  • 5HT transporter
  • Na+/Cl- dependent serotonin transporter
  • serotonin transporter 1
  • sodium-dependent serotonin transporter
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • 5HTT
  • Sodium-dependent serotonin transporter (5HT transporter) (5HTT)
  • solute carrier family 6 member 4
  • Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter)
  • serotonin transporter
  • solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter)
  • solute carrier family 6, member 4
  • CG4545-PA
  • SerT-PA
  • drosophila serotonin transporter
  • cocaine-sensitive serotonin transporter
  • plasma membrane transporter for serotonin reuptake
  • transmembrane 5-HT transporter
  • sodium-dependent serotonin transporter-like
  • huntingtin
  • serotnin transporter
  • serotonin transporter b
  • sertb
  • solute carrier family 6 (neurotransmitter transporter), member 4b
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4B
  • serotonin transporter a
  • serta
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4A
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