SNAP23 Products
(Synaptosomal-Associated Protein, 23kDa (SNAP23))
Categories
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Featured SNAP23 Categories
SNAP23 Antibodies
High quality antibodies with extensive validation data.
SNAP23 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SNAP23 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7444214
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7444226
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (5)
Cat. No.
ABIN563782
Quantity
100 μg
Datasheet
Datasheet
Recommended SNAP23 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6221616
Quantity
96 tests
Datasheet
Datasheet
Recommended SNAP23 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320745
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN934997
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505232
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SNAP23 products
: "Phosphorylation of syntaxin-3 at Thr 14 negatively regulates exocytosis in RBL-2H3 mast cells." in: Cell biology international, Vol. 40, Issue 5, pp. 589-96, (2016) (PubMed).: "Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 8, pp. 3413-23, (2013) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).
: "The SNARE protein SNAP23 and the SNARE-interacting protein Munc18c in human skeletal muscle are implicated in insulin resistance/type 2 diabetes." in: Diabetes, Vol. 59, Issue 8, pp. 1870-8, (2010) (PubMed).
: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and ..." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, (2009) (PubMed).
Synonyms and alternative names related to SNAP23
synaptosome associated protein 23 (SNAP23), synaptosome associated protein 23kDa (snap23), synaptosomal-associated protein 23 (Snap23), synaptosome associated protein 23 (Snap23), synaptosome associated protein 23kDa L homeolog (snap23.L), 23kDa, AA408749, HsT17016, SNAP-23, snap23-A, SNAP23A, SNAP23B, Sndt, Syndet, XOSNAP-23Protein level used designations for SNAP23
- synaptosomal-associated protein 23
- synaptosomal-associated protein 23 isoform SNAP23A
- synaptosomal-associated protein, 23kDa
- synaptosomal-associated protein, 23kD
- vesicle-membrane fusion protein SNAP-23
- SNAP-23
- synaptosomal-associated protein 23 kD
- synaptosomal-associated protein, 23 kD
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