SMURF1 Products
(SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
Categories
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010].
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Featured SMURF1 Categories
SMURF1 Antibodies
High quality antibodies with extensive validation data.
SMURF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SMURF1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMURF1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF, IP
Validations
- (2)
- (10)
Cat. No.
ABIN566098
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (5)
Cat. No.
ABIN7151222
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (4)
- (4)
Cat. No.
ABIN388828
Quantity
400 μL
Datasheet
Datasheet
Recommended SMURF1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975573
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1131325
Quantity
96 tests
Datasheet
Datasheet
Recommended SMURF1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1320726
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320727
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095593
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SMURF1 products
: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).: "Glucocorticoid-induced leucine zipper (GILZ) antagonizes TNF-? inhibition of mesenchymal stem cell osteogenic differentiation." in: PLoS ONE, Vol. 7, Issue 3, pp. e31717, (2012) (PubMed).
: "Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 7, pp. 805-13, (2010) (PubMed).
: "Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23084-92, (2008) (PubMed).
: "The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity." in: The Journal of biological chemistry, Vol. 282, Issue 48, pp. 35259-68, (2007) (PubMed).
: "Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity." in: The EMBO journal, Vol. 26, Issue 5, pp. 1410-22, (2007) (PubMed).
: "Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts." in: The Journal of biological chemistry, Vol. 281, Issue 7, pp. 4326-33, (2006) (PubMed).
: "Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1603-9, (2005) (PubMed).
Synonyms and alternative names related to SMURF1
SMAD specific E3 ubiquitin protein ligase 1 (SMURF1), E3 ubiquitin-protein ligase SMURF1 (LOC100540915), SMAD specific E3 ubiquitin protein ligase 1 (smurf1), SMAD specific E3 ubiquitin protein ligase 1 (Smurf1), SMAD specific E3 ubiquitin protein ligase 1 L homeolog (smurf1.L), 4930431E10Rik, mKIAA1625, RGD1309707Protein level used designations for SMURF1
- Smad ubiquitination regulatory factor 1
- E3 ubiquitin-protein ligase SMURF1
- SMAD specific E3 ubiquitin protein ligase 1
- e3 ubiquitin-protein ligase SMURF1-like
- E3 ubiquitin ligase SMURF1
- SMAD-specific E3 ubiquitin-protein ligase 1
- Smad-specific E3 ubiquitin ligase 1
- hSMURF1
- SMAD ubiquitination regulatory factor 1
- xSMURF1
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