SMPD1 Products
(Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
Categories
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010].
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Featured SMPD1 Categories
SMPD1 Antibodies
High quality antibodies with extensive validation data.
SMPD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SMPD1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMPD1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN656161
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7433534
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN6148144
Quantity
100 μL
Datasheet
Datasheet
Recommended SMPD1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6959671
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6974222
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962045
Quantity
96 tests
Datasheet
Datasheet
Recommended SMPD1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320696
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320698
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7198103
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our SMPD1 products
: "Fenofibrate decreases plasma ceramide in type 2 diabetes patients: A novel marker of CVD?" in: Diabetes & metabolism, Vol. 44, Issue 2, pp. 143-149, (2018) (PubMed).: "Heat shock protein 70.1 (Hsp70.1) affects neuronal cell fate by regulating lysosomal acid sphingomyelinase." in: The Journal of biological chemistry, Vol. 289, Issue 40, pp. 27432-43, (2014) (PubMed).
: "Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD." in: Blood, Vol. 124, Issue 12, pp. 1941-50, (2014) (PubMed).
: "Sphingosine mediates TNF?-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells." in: Journal of lipid research, Vol. 53, Issue 6, pp. 1134-43, (2012) (PubMed).
: "Ebolavirus requires acid sphingomyelinase activity and plasma membrane sphingomyelin for infection." in: Journal of virology, Vol. 86, Issue 14, pp. 7473-83, (2012) (PubMed).
: "Human acid sphingomyelinase." in: European journal of biochemistry / FEBS, Vol. 270, Issue 6, pp. 1076-88, (2003) (PubMed).
Synonyms and alternative names related to SMPD1
sphingomyelin phosphodiesterase 1 (SMPD1), sphingomyelin phosphodiesterase 1, acid lysosomal (Smpd1), sphingomyelin phosphodiesterase (LOC5578088), sphingomyelin phosphodiesterase 1 (Smpd1), sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), A-SMase, ASM, ASMASE, aSMase, NPD, SMPD1, Zn-SMaseProtein level used designations for SMPD1
- acid sphingomyelinase
- sphingomyelin phosphodiesterase
- sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase)
- aSMase
- sphingomyelin phosphodiesterase 1, acid lysosomal
- sphingomyelin phosphodiesterase 1
- sphingomyelin phosphodiesterase-like
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