SMO Products
(Smoothened Homolog (Drosophila) (SMO))
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The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010].
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Featured SMO Categories
SMO Antibodies
High quality antibodies with extensive validation data.
SMO ELISA Kits
Reliable ELISA kits for a wide range of species.
SMO Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMO Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (p)
Validations
- (3)
- (4)
Cat. No.
ABIN680908
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6148140
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7169898
Quantity
100 μg
Datasheet
Datasheet
Recommended SMO ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959535
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959536
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Sandwich ELISA
Validations
Cat. No.
ABIN418558
Quantity
96 tests
Datasheet
Datasheet
Recommended SMO Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320686
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320688
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320690
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SMO products
: "GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment." in: Scientific reports, Vol. 7, Issue 1, pp. 13379, (2019) (PubMed).: "Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 3, pp. 1129-40, (2016) (PubMed).
: "Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling." in: Chemico-biological interactions, Vol. 228, pp. 100-7, (2015) (PubMed).
: "Identification of recurrent SMO and BRAF mutations in ameloblastomas." in: Nature genetics, Vol. 46, Issue 7, pp. 722-5, (2014) (PubMed).
: "SMO expression level correlates with overall survival in patients with malignant pleural mesothelioma." in: Journal of experimental & clinical cancer research : CR, Vol. 32, pp. 7, (2013) (PubMed).
: "Structure of the human smoothened receptor bound to an antitumour agent." in: Nature, Vol. 497, Issue 7449, pp. 338-43, (2013) (PubMed).
: "Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling." in: Nature communications, Vol. 4, pp. 2965, (2013) (PubMed).
: "Overexpression of Hedgehog signaling molecules and its involvement in triple-negative breast cancer." in: Oncology letters, Vol. 2, Issue 5, pp. 995-1001, (2012) (PubMed).
: "Role of Sonic Hedgehog in idiopathic pulmonary fibrosis." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 303, Issue 11, pp. L978-90, (2012) (PubMed).
: "Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancer-associated fibroblasts." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 6, pp. 1781-9, (2010) (PubMed).
Synonyms and alternative names related to SMO
smoothened, frizzled class receptor (SMO), smoothened, frizzled class receptor (Smo), smoothened, frizzled class receptor L homeolog (smo.L), smoothened, frizzled class receptor (smo), bnb, E130215L21Rik, FZD11, Gx, SMOH, Smoh, smoothened, XSmoProtein level used designations for SMO
- frizzled family member 11
- protein Gx
- seven transmembrane helix receptor
- smoothened homolog
- smoothened, seven transmembrane spanning receptor
- bent body
- X-smoothened
- smoothened, frizzled family receptor
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