SMG8 Products
(Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
Categories
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity (By similarity).
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Featured SMG8 Categories
SMG8 Antibodies
High quality antibodies with extensive validation data.
Recommended SMG8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7238174
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6744122
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN632938
Quantity
100 μL
Datasheet
Datasheet
Recommended SMG8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095590
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136728
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to SMG8
SMG8, nonsense mediated mRNA decay factor (SMG8), smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg8), Protein smg-8 (smg-8), 1200011M11Rik, C17orf71, C19H17orf71Protein level used designations for SMG8
- amplified in breast cancer gene 2 protein
- protein SMG8
- protein smg-8 homolog
- smg-8 homolog, nonsense mediated mRNA decay factor
- CG6729 gene product
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