SMC5 Products
(Structural Maintenance of Chromosomes 5 (SMC5))
Categories
Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression\; the function seems to be independent of SMC6 (By similarity).
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Featured SMC5 Categories
SMC5 Antibodies
High quality antibodies with extensive validation data.
SMC5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMC5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (2)
Cat. No.
ABIN570758
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN1682829
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7170870
Quantity
100 μg
Datasheet
Datasheet
Recommended SMC5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210878
Quantity
96 tests
Datasheet
Datasheet
Recommended SMC5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320663
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095581
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136442
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SMC5 products
: "SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes." in: Development (Cambridge, England), Vol. 144, Issue 9, pp. 1648-1660, (2017) (PubMed).: "Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 1, pp. M110.000703, (2011) (PubMed).
: "Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 37, pp. 15726-31, (2009) (PubMed).
: "Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4099-109, (2008) (PubMed).
Synonyms and alternative names related to SMC5
structural maintenance of chromosomes 5 (SMC5), structural maintenance of chromosomes 5 (smc5), structural maintenance of chromosomes 5 (Smc5), structural maintenance of chromosomes 5 S homeolog (smc5.S), F1N13.60, F1N13_60, mKIAA0594, MLZ-453, mSMC5, SMC-5, SMC5L1, Smc5l1, structural maintenance of chromosomes 5Protein level used designations for SMC5
- SMC protein 5
- structural maintenance of chromosomes protein 5
- SMC-5
- SMC5 structural maintenance of chromosomes 5-like 1
- hSMC5
- protein expressed in male leptotene and zygotene spermatocytes 453
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