SMC3 Products
(Structural Maintenance of Chromosomes 3 (SMC3))
Categories
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008].
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Featured SMC3 Categories
SMC3 Antibodies
High quality antibodies with extensive validation data.
SMC3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMC3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7440092
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN6265185
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN522580
Quantity
50 μL
Datasheet
Datasheet
Recommended SMC3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6211766
Quantity
96 tests
Datasheet
Datasheet
Recommended SMC3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320659
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406332
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095549
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our SMC3 products
: "A Novel Role for α-Importins and Akirin in Establishment of Meiotic Sister Chromatid Cohesion in Caenorhabditis elegans." in: Genetics, Vol. 211, Issue 2, pp. 617-635, (2019) (PubMed).: "HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. ..." in: Nature, Vol. 489, Issue 7415, pp. 313-7, (2012) (PubMed).
: "Two different replication factor C proteins, Ctf18 and RFC1, separately control PCNA-CRL4Cdt2-mediated Cdt1 proteolysis during S phase and following UV irradiation." in: Molecular and cellular biology, Vol. 32, Issue 12, pp. 2279-88, (2012) (PubMed).
: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).
: "Cohesin SMC1beta protects telomeres in meiocytes." in: The Journal of cell biology, Vol. 187, Issue 2, pp. 185-99, (2009) (PubMed).
: "Cohesin acetylation speeds the replication fork." in: Nature, Vol. 462, Issue 7270, pp. 231-4, (2009) (PubMed).
: "Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates." in: Molecular cell, Vol. 18, Issue 2, pp. 185-200, (2005) (PubMed).
: "Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination." in: Nature cell biology, Vol. 6, Issue 6, pp. 555-62, (2004) (PubMed).
Synonyms and alternative names related to SMC3
structural maintenance of chromosomes 3 (smc3), structural maintenance of chromosomes 3 (SMC3), structural maintenance of chromosomes 3 (Smc3), structural maintenance of chromosomes 3 S homeolog (smc3.S), BAM, Bamacan, bamacan, BMH, CDLS3, cspg6, CSPG6, Cspg6, HCAP, im:7142991, Mmip1, SMC-3, SMC3L1, SmcD, wu:fb22e01, wu:fc30d07, xsmc3Protein level used designations for SMC3
- chondroitin sulfate proteoglycan 6 (bamacan)
- SMC protein 3
- basement membrane-associated chondroitin proteoglycan
- chromosome-associated polypeptide
- structural maintenance of chromosomes protein 3
- chondroitin sulfate proteoglycan 6
- chromosome segregation protein SmcD
- mad member-interacting protein 1
- structural maintenace of chromosomes 3
- cohesin complex subunit
- bamacan
- basement membrane chondroitin sulfate proteoglycan
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