SMARCA2 Products
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2))
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The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jul 2008].
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Featured SMARCA2 Categories
SMARCA2 Antibodies
High quality antibodies with extensive validation data.
SMARCA2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMARCA2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, ChIP
Validations
- (3)
Cat. No.
ABIN7164521
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN520280
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6736031
Quantity
100 μL
Datasheet
Datasheet
Recommended SMARCA2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320621
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN2669725
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN2669697
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SMARCA2 products
: "Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 29, Issue 1, pp. 60-6, (2015) (PubMed).: "Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome. ..." in: Nature genetics, Vol. 44, Issue 4, pp. 445-9, S1, (2012) (PubMed).
: "Generation of a rat monoclonal antibody specific for Brm." in: Hybridoma (2005), Vol. 28, Issue 6, pp. 455-8, (2009) (PubMed).
: "SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7422-30, (2003) (PubMed).
: "SWI/SNF chromatin remodelling complex and retroviral gene silencing." in: Reviews in medical virology, Vol. 13, Issue 2, pp. 99-110, (2003) (PubMed).
: "SWI/SNF chromatin remodeling and cancer." in: Current opinion in genetics & development, Vol. 12, Issue 1, pp. 73-9, (2002) (PubMed).
: "Maintenance of integrated proviral gene expression requires Brm, a catalytic subunit of SWI/SNF complex." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 15859-64, (2002) (PubMed).
: "BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines." in: Cancer research, Vol. 60, Issue 21, pp. 6171-7, (2000) (PubMed).
: "The Swi/Snf family nucleosome-remodeling complexes and transcriptional control." in: Trends in genetics : TIG, Vol. 16, Issue 8, pp. 345-51, (2000) (PubMed).
: "A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor." in: Nature, Vol. 374, Issue 6522, pp. 562-5, (1995) (PubMed).
Synonyms and alternative names related to SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 L homeolog (smarca2.L), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (Smarca2), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (smarca2), 2610209L14Rik, BAF190, brahma, Brahma, BRM, brm, hBRM, hSNF2a, NCBRS, psa-4, SNF2, SNF2alpha, SNF2L2, Snf2l2, SNF2LA, Sth1p, SWI2, wu:fa56c07, wu:fi27f11, zgc:66238Protein level used designations for SMARCA2
- ATP-dependent helicase SMARCA2
- BAF190B
- BRG1-associated factor 190B
- SNF2-alpha
- SNF2/SWI2-like protein 2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2
- global transcription activator homologous sequence
- probable global transcription activator SNF2L2
- protein brahma homolog
- sucrose nonfermenting 2-like protein 2
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
- subunit of the SWI/SNF chromatin remodeling complex
- phasmid Socket Absent PSA-4
Did you look for something else?
- SMARCA1
- SMAP2
- SMAP1
- Small Ubiquitin Related Modifier Protein 1
- Small Ubiquitin Related Modifier 3
- Small Proline-Rich Protein 2B
- Small Nuclear RNA Activating Complex, Polypeptide 1, 43kDa
- Small Nuclear Ribonucleoprotein Polypeptide A
- Small Integral Membrane Protein 12
- Small Cajal Body-Specific RNA 22
- SMAGP
- SMAD9
- SMAD7
- SMAD6
- SMAD5-AS1
- SMAD5
- SMAD4
- Smad2/3
- SMAD2
- Smad1/9
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