SMAD7 Products
(SMAD, Mothers Against DPP Homolog 7 (SMAD7))
Categories
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
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Featured SMAD7 Categories
SMAD7 Antibodies
High quality antibodies with extensive validation data.
SMAD7 ELISA Kits
Reliable ELISA kits for a wide range of species.
SMAD7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMAD7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS
Validations
- (3)
- (5)
Cat. No.
ABIN670206
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN517666
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN517661
Quantity
100 μg
Datasheet
Datasheet
Recommended SMAD7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959527
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970256
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970255
Quantity
96 tests
Datasheet
Datasheet
Recommended SMAD7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320614
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7391504
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7391501
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our SMAD7 products
: "Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis." in: Gastroenterology, Vol. 156, Issue 3, pp. 692-707.e7, (2019) (PubMed).: "MicroRNA-15a inhibition protects against hypoxia/reoxygenation-induced apoptosis of cardiomyocytes by targeting mothers against decapentaplegic homolog 7." in: Molecular medicine reports, Vol. 15, Issue 6, pp. 3699-3705, (2017) (PubMed).
: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).
: "MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST." in: Cell death & disease, Vol. 7, pp. e2203, (2016) (PubMed).
: "Transforming growth factor-β1 SMAD effectors and medial cell number in ascending aorta diseases." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 25, Issue 3, pp. 240-6, (2016) (PubMed).
: "Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats." in: Scientific reports, Vol. 6, pp. 39809, (2016) (PubMed).
: "Immunoexpression of TGF-β/Smad and VEGF-A proteins in serum and BAL fluid of sarcoidosis patients." in: BMC immunology, Vol. 16, pp. 58, (2015) (PubMed).
: "Synchronous alteration pattern between serine-threonine kinase receptor-associated protein and Smad7 in pilocarpine-induced rats of epilepsy." in: Synapse (New York, N.Y.), Vol. 68, Issue 6, pp. 275-82, (2014) (PubMed).
: "MG132 ameliorates kidney lesions by inhibiting the degradation of Smad7 in streptozotocin-induced diabetic nephropathy." in: Journal of diabetes research, Vol. 2014, pp. 918396, (2014) (PubMed).
: "Retinoic acid induced repair in the lung of adult hyperoxic mice, reducing transforming growth factor-β1 (TGF-β1) mediated abnormal alterations." in: Acta histochemica, Vol. 116, Issue 5, pp. 810-9, (2014) (PubMed).
Synonyms and alternative names related to SMAD7
SMAD family member 7 (SMAD7), SMAD family member 7 (Smad7), SMAD family member 7 L homeolog (smad7.L), SMAD family member 7 (smad7), CRCS3, MADH7, Madh7, madh7, MADH8, Smad7a, Smad10, wu:fj60c10, xsmad7Protein level used designations for SMAD7
- MAD (mothers against decapentaplegic, Drosophila) homolog 7
- MAD homolog 8
- Mothers against decapentaplegic, drosophila, homolog of, 7
- SMAD, mothers against DPP homolog 7
- hSMAD7
- mothers against DPP homolog 8
- mothers against decapentaplegic homolog 7
- SMAD family member 7
- MAD homolog 7
- SMAD 7
- madh8
- mothers against DPP homolog 7
- mothers against decapentaplegic homolog 8
- mothers against DPP 7
- mothers against decapentaplegic-like protein 7
- MAD, mothers against decapentaplegic homolog 7
- fj60c10
Did you look for something else?
- SMAD6
- SMAD5-AS1
- SMAD5
- SMAD4
- Smad2/3
- SMAD2
- Smad1/9
- SMAD1/5/8/9
- Smad1/5
- SMAD1
- SMAD, Mothers Against DPP Homolog 3
- SLYX
- SLX9
- SLX4IP
- SLX1A/GIYD2
- SLX1 Structure-Specific Endonuclease Subunit Homolog A (S. Cerevisiae)
- SLURP1
- SLUG
- SLUG
- SLU7
- SMAD9
- SMAGP
- Small Cajal Body-Specific RNA 22
- Small Integral Membrane Protein 12
- Small Nuclear Ribonucleoprotein Polypeptide A
- Small Nuclear RNA Activating Complex, Polypeptide 1, 43kDa
- Small Proline-Rich Protein 2B
- Small Ubiquitin Related Modifier 3
- Small Ubiquitin Related Modifier Protein 1
- SMAP1
- SMAP2
- SMARCA1
- SMARCA2
- SMARCA4
- SMARCA5
- SMARCAD1
- SMARCAL1
- SMARCB1
- SMARCC1
- SMARCC2
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