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SMAD6 Products

(SMAD, Mothers Against DPP Homolog 6 (SMAD6))

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The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009].

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Featured SMAD6 Categories

SMAD6 Antibodies

High quality antibodies with extensive validation data.

SMAD6 ELISA Kits

Reliable ELISA kits for a wide range of species.

SMAD6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SMAD6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP, IF
Validations
  • (4)
Cat. No. ABIN948096
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN517653
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN517658
Quantity 100 μg
Datasheet Datasheet

Recommended SMAD6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN585471
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN585472
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1143179
Quantity 96 tests
Datasheet Datasheet

Recommended SMAD6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320612
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1989691
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413859
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SMAD6 products

Xu, Xu, Saud, Lu, Liu, Fang, Zhang, Hu, Li: "Effect of Kuijie Granule on the Expression of TGF-β/Smads Signaling Pathway in Patients with Ulcerative Colitis." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 2601830, (2016) (PubMed).

Frullanti, Colombo, Falvella, Galvan, Noci, De Cecco, Incarbone, Alloisio, Santambrogio, Nosotti, Tosi, Pastorino, Dragani: "Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue." in: International journal of cancer. Journal international du cancer, Vol. 131, Issue 5, pp. E643-8, (2012) (PubMed).

Ryan, Ryan, Fabre, Lawless, Crowe: "Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1266-73, (2010) (PubMed).

Hogg, Etherington, Young, McNeilly, Duncan: "Inhibitor of differentiation (Id) genes are expressed in the steroidogenic cells of the ovine ovary and are differentially regulated by members of the transforming growth factor-beta family." in: Endocrinology, Vol. 151, Issue 3, pp. 1247-56, (2010) (PubMed).

Childs, Kinnell, Collins, Hogg, Bayne, Green, McNeilly, Anderson: "BMP signaling in the human fetal ovary is developmentally regulated and promotes primordial germ cell apoptosis." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 8, pp. 1368-78, (2010) (PubMed).

Yu, Mrowietz, Seifert: "Downregulation of SMAD2, 4 and 6 mRNA and TGFbeta receptor I mRNA in lesional and non-lesional psoriatic skin." in: Acta dermato-venereologica, Vol. 89, Issue 4, pp. 351-6, (2009) (PubMed).

Shintani, Yagi, Nakayama, Saji, Matsuoka: "A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension." in: Journal of medical genetics, Vol. 46, Issue 5, pp. 331-7, (2009) (PubMed).

Wang, Wei, Zhu, Zhang, Shen, Xing, OKeefe, Chen: "Bone morphogenetic protein 2 activates Smad6 gene transcription through bone-specific transcription factor Runx2." in: The Journal of biological chemistry, Vol. 282, Issue 14, pp. 10742-8, (2007) (PubMed).

Yoshiura, Ohtsuka, Takenaka, Nagahara, Yoshikawa, Kageyama: "Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 27, pp. 11292-7, (2007) (PubMed).

Shen, Chen, Wang, Kaneki, Xing, Okeefe, Chen: "Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation." in: The Journal of biological chemistry, Vol. 281, Issue 6, pp. 3569-76, (2006) (PubMed).

Synonyms and alternative names related to SMAD6

SMAD family member 6 (smad6), SMAD family member 6 (SMAD6), SMAD family member 6 (Smad6), SMAD family member 6a (smad6a), AOVD2, b2b390Clo, hst17432, HsT17432, madh6, MADH6, Madh6, madh7, MADH7, smad6, Smad6-like, wu:fb22g05, Xsmad6

Protein level used designations for SMAD6

  • SMAD, mothers against DPP homolog 6
  • MAD homolog 6
  • Mothers against decapentaplegic, drosophila, homolog of, 6
  • SMAD 6
  • hSMAD6
  • mothers against DPP homolog 6
  • mothers against decapentaplegic homolog 6
  • Smad 6
  • mad homolog 7
  • MAD, mothers against decapentaplegic homolog 6
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