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SMAD4 Proteins

(SMAD Family Member 4 (SMAD4))

This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009].

recommended

SMAD4 Protein (AA 1-552) (GST tag) (ABIN1320605)

SMAD4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

SMAD4 Protein (AA 13-227) (His tag) (ABIN7125119)

SMAD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

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recommended

SMAD4 Protein (AA 56-165) (GST tag) (ABIN1320607)

SMAD4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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SMAD4 Proteins by Origin

Find SMAD4 Proteins for a variety of species such as anti-Human SMAD4, anti-Mouse SMAD4, anti-Rat SMAD4. The species listed below are among those available. Click on a link to go to the corresponding products.

SMAD4 Proteins by Source

Here you will find SMAD4 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SMAD4 Proteins by Protein Type

Here you can find SMAD4 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SMAD4 Proteins by Application

Find SMAD4 Proteins validated for a specific application such as WB, ELISA, SDS, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SMAD4 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SMAD4 Protein (AA 1-552) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1320605

Quantity 10 μg

Datasheet Datasheet

SMAD4 Protein (AA 13-227) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125119

Quantity 50 μg

Datasheet Datasheet

SMAD4 Protein (AA 56-165) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1320607

Quantity 10 μg

Datasheet Datasheet

SMAD4 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2732222

Quantity 20 μg

Datasheet Datasheet

SMAD4 Protein (AA 1-552) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1692097

Quantity 50 μg

Datasheet Datasheet

SMAD4 Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7319042

Quantity 50 μg

Datasheet Datasheet

SMAD4 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2131868

Quantity 100 μg

Datasheet Datasheet

SMAD4 Protein (AA 323-552) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7395287

Quantity 100 μg

Datasheet Datasheet

SMAD4 Protein (AA 9-231) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7413811

Quantity 100 μg

Datasheet Datasheet

SMAD4 Protein (AA 1-551) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3134713

Quantity 1 mg

Datasheet Datasheet

SMAD4 Protein (AA 1-552) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3095493

Quantity 1 mg

Datasheet Datasheet

SMAD4 Protein

Reactivity Human, Mouse, Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2751533

Quantity 5 applications

Datasheet Datasheet

SMAD4 Protein (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6700538

Quantity 50 μg

Datasheet Datasheet

SMAD4 Protein (AA 1-552) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1475622

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our SMAD4 Proteins

Atanelishvili, Shirai, Akter, Buckner, Noguchi, Silver, Bogatkevich: "M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo." in: Translational research : the journal of laboratory and clinical medicine, Vol. 170, pp. 99-111, (2016) (PubMed).

Iempridee, Das, Xu, Mertz: "Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene." in: Journal of virology, Vol. 85, Issue 15, pp. 7836-48, (2011) (PubMed).

Aliases for SMAD4 Proteins

SMAD family member 4 (SMAD4) Proteins
Smad4 protein (smad4) Proteins
SMAD family member 4 (Smad4) Proteins
SMAD family member 4, gene 1 L homeolog (smad4.1.L) Proteins
AW743858 Proteins
D18Wsu70e Proteins
DPC4 Proteins
dpc4 Proteins
JIP Proteins
jip Proteins
MADH4 Proteins
Madh4 Proteins
madh4 Proteins
MYHRS Proteins
smad4 Proteins
Xsmad4 Proteins
xsmad4a Proteins
XSmad4alpha Proteins

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SMAD4 Proteins by Origin

SMAD4 Proteins by Source

SMAD4 Proteins by Protein Type

SMAD4 Proteins by Application

Popular SMAD4 Proteins

Latest Publications for our SMAD4 Proteins

Aliases for SMAD4 Proteins

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