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SMAD2 Proteins

(SMAD, Mothers Against DPP Homolog 2 (SMAD2))

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012].

recommended

SMAD2 Protein (AA 181-280) (GST tag) (ABIN1320595)

SMAD2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

SMAD2 Protein (AA 2-467) (His tag) (ABIN7125122)

SMAD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

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recommended

SMAD2 Protein (AA 1-467) (His tag) (ABIN667736)

SMAD2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS

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SMAD2 Proteins by Origin

Find SMAD2 Proteins for a variety of species such as anti-Human SMAD2, anti-Mouse SMAD2, anti-Cow SMAD2. The species listed below are among those available. Click on a link to go to the corresponding products.

SMAD2 Proteins by Source

Here you will find SMAD2 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

SMAD2 Proteins by Protein Type

Here you can find SMAD2 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

SMAD2 Proteins by Application

Find SMAD2 Proteins validated for a specific application such as ELISA, SDS, WB, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular SMAD2 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SMAD2 Protein (AA 181-280) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1320595

Quantity 10 μg

Datasheet Datasheet

SMAD2 Protein (AA 2-467) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125122

Quantity 50 μg

Datasheet Datasheet

SMAD2 Protein (AA 1-467) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN667736

Quantity 100 μg

Datasheet Datasheet

SMAD2 Protein (GST tag,His tag)

Reactivity Mouse

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN7320169

Quantity 100 μg

Datasheet Datasheet

SMAD2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2732219

Quantity 20 μg

Datasheet Datasheet

SMAD2 Protein (AA 272-467) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7395908

Quantity 100 μg

Datasheet Datasheet

SMAD2 Protein (AA 274-467) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7401368

Quantity 100 μg

Datasheet Datasheet

SMAD2 Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2131866

Quantity 100 μg

Datasheet Datasheet

SMAD2 Protein (AA 2-467, full length) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1047400

Quantity 50 μg

Datasheet Datasheet

SMAD2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2732220

Quantity 20 μg

Datasheet Datasheet

SMAD2 Protein (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6700544

Quantity 50 μg

Datasheet Datasheet

SMAD2 Protein

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6307034

Quantity 1 mg

Datasheet Datasheet

SMAD2 Protein (AA 2-467) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1475773

Quantity 1 mg

Datasheet Datasheet

SMAD2 Protein (AA 2-467) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1620647

Quantity 1 mg

Datasheet Datasheet

SMAD2 Protein (AA 1-468) (His tag)

Reactivity Zebrafish (Danio rerio)

Source Yeast

Validations

Cat. No. ABIN1653533

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our SMAD2 Proteins

Atanelishvili, Shirai, Akter, Buckner, Noguchi, Silver, Bogatkevich: "M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo." in: Translational research : the journal of laboratory and clinical medicine, Vol. 170, pp. 99-111, (2016) (PubMed).

Aliases for SMAD2 Proteins

SMAD family member 2 (SMAD2) Proteins
SMAD family member 2-Z (SMAD2Z) Proteins
SMAD family member 2 (smad2) Proteins
SMAD family member 2 S homeolog (smad2.S) Proteins
SMAD family member 2 (Smad2) Proteins
7120426M23Rik Proteins
fj43c06 Proteins
hMAD-2 Proteins
hmad-2 Proteins
hSMAD2 Proteins
hsmad2 Proteins
JV18 Proteins
jv18 Proteins
JV18-1 Proteins
jv18-1 Proteins
MADH2 Proteins
madh2 Proteins
Madh2 Proteins
MAD homolog 2 Proteins
MADR2 Proteins
madr2 Proteins
Madr2 Proteins
mMad2 Proteins
Mothers against DPP homolog 2 Proteins
smad-2 Proteins
Smad-2 Proteins
SMAD 2 Proteins
Smad2 Proteins
wu:fj43c06 Proteins
Xmad2 Proteins
XSmad2 Proteins

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SMAD2 Proteins by Origin

SMAD2 Proteins by Source

SMAD2 Proteins by Protein Type

SMAD2 Proteins by Application

Popular SMAD2 Proteins

Latest Publications for our SMAD2 Proteins

Aliases for SMAD2 Proteins

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