SMAD1 Products
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
Categories
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
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Featured SMAD1 Categories
SMAD1 Antibodies
High quality antibodies with extensive validation data.
SMAD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SMAD1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SMAD1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (1)
- (9)
Cat. No.
ABIN517610
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (7)
Cat. No.
ABIN3021439
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (7)
Cat. No.
ABIN517611
Quantity
100 μg
Datasheet
Datasheet
Recommended SMAD1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959518
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970248
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970247
Quantity
96 tests
Datasheet
Datasheet
Recommended SMAD1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1320591
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125121
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320593
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SMAD1 products
: "Hyaluronan negatively regulates vascular calcification involving BMP2 signaling." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 98, Issue 10, pp. 1320-1332, (2018) (PubMed).: "Tcf12, A Member of Basic Helix-Loop-Helix Transcription Factors, Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation In Vitro and In Vivo." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 2, pp. 386-397, (2017) (PubMed).
: "MiR-199a-3p suppresses proliferation and invasion of prostate cancer cells by targeting Smad1." in: Oncotarget, Vol. 8, Issue 32, pp. 52465-52473, (2017) (PubMed).
: "NLRC5 Mediates IL-6 and IL-1? Secretion in LX-2 Cells and Modulated by the NF-?B/Smad3 Pathway." in: Inflammation, Vol. 38, Issue 5, pp. 1794-804, (2015) (PubMed).
: "Camel milk attenuates the biochemical and morphological features of diabetic nephropathy: inhibition of Smad1 and collagen type IV synthesis." in: Chemico-biological interactions, Vol. 229, pp. 100-8, (2015) (PubMed).
: "Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia." in: Journal of the neurological sciences, Vol. 337, Issue 1-2, pp. 25-37, (2014) (PubMed).
: "Simultaneous imaging and restoration of cell function using cell permeable peptide probe." in: Biomaterials, Vol. 35, Issue 24, pp. 6287-98, (2014) (PubMed).
: "Dexamethasone attenuates bleomycin-induced lung fibrosis in mice through TGF-?, Smad3 and JAK-STAT pathway." in: International journal of clinical and experimental medicine, Vol. 7, Issue 9, pp. 2645-50, (2014) (PubMed).
: "Tranilast prevents the progression of chronic cyclosporine nephrotoxicity through regulation of transforming growth factor ?/Smad pathways." in: Transplantation proceedings, Vol. 43, Issue 5, pp. 1985-8, (2011) (PubMed).
: "Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-? cytostatic program and blocks the antiproliferative effect of TGF-?." in: Oncogene, Vol. 30, Issue 24, pp. 2718-29, (2011) (PubMed).
Synonyms and alternative names related to SMAD1
SMAD family member 1 (smad1), SMAD family member 1 (SMAD1), Mothers against dpp (Mad), SMAD family member 1 (Smad1), SMAD family member 1 L homeolog (smad1.L), 2/23, AI528653, apg, BSP-1, bsp1, BSP1, c28, CG12399, dMAD, dMad, Dmel\\CG12399, E(zen)2, En(vvl), fb39h09, jv4-1, JV4-1, jv41, JV41, l(2)K00237, l(2)k00237, MAD, mad, madh1, MADH1, Madh1, madr1, MADR1, Madr1, Mat, MLP, Mlp1, MusMLP, P-Mad, P-mad, p-Mad, PMad, pMAD, pMad, pSmad, Smad, smad-1, Smad1, smad1, wu:fb39h09, wu:fb97e04, xmad, Xmad1, Xsmad1Protein level used designations for SMAD1
- MAD homolog 1
- SMAD, mothers against DPP homolog 1
- mothers against decapentaplegic homolog 1
- mothers against decapentaplegic-like protein 1
- MAD (mothers against decapentaplegic, Drosophila) homolog 1
- SMA- and MAD-related protein 1
- SMAD 1
- SMAD family member 1
- mothers against DPP homolog 1
- CG12399-PA
- CG12399-PB
- Mad-PA
- Mad-PB
- apang
- mother against decapentaplegic
- mothers against decapentaplegi
- mothers against decapentaplegic
- mothers against dpp
- phospho-Smad
- phosphoSmad
- phosphorylated smad
- MAD, mothers against decapentaplegic homolog 1
- Mad-related protein 1
- TGF-beta signaling protein 1
- transforming growth factor-beta signaling protein 1
- transforming growth factor-beta-signaling protein 1
- Smad 1
- dwarfin-A
- dwf-A
- mMad1
- mad-related protein 1
- mothers-against-DPP-related 1
- MAD homolog1 (mothers against decapentaplegic, Drosophila)
- mothers against DPP
- BMP pathway effector
- BMP signal transducer Smad1
- Sma- and Mad-related protein 1
Did you look for something else?
- SMAD, Mothers Against DPP Homolog 3
- SLYX
- SLX9
- SLX4IP
- SLX1A/GIYD2
- SLX1 Structure-Specific Endonuclease Subunit Homolog A (S. Cerevisiae)
- SLURP1
- SLUG
- SLUG
- SLU7
- SLTM
- SLPI
- SLN13
- SLN
- SLMO2
- SLMO1/PRELID3A
- SLK
- SLITRK6
- SLITRK5
- SLITRK4
- Smad1/5
- SMAD1/5/8/9
- Smad1/9
- SMAD2
- Smad2/3
- SMAD4
- SMAD5
- SMAD5-AS1
- SMAD6
- SMAD7
- SMAD9
- SMAGP
- Small Cajal Body-Specific RNA 22
- Small Integral Membrane Protein 12
- Small Nuclear Ribonucleoprotein Polypeptide A
- Small Nuclear RNA Activating Complex, Polypeptide 1, 43kDa
- Small Proline-Rich Protein 2B
- Small Ubiquitin Related Modifier 3
- Small Ubiquitin Related Modifier Protein 1
- SMAP1
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