SLPI Products
(Secretory Leukocyte Peptidase Inhibitor (SLPI))
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This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes\; the protein is also thought to have broad-spectrum anti-biotic activity. [provided by RefSeq, Jul 2008].
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Featured SLPI Categories
SLPI Antibodies
High quality antibodies with extensive validation data.
SLPI ELISA Kits
Reliable ELISA kits for a wide range of species.
SLPI Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLPI Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7433429
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7144333
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN520270
Quantity
100 μg
Datasheet
Datasheet
Recommended SLPI ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959320
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959321
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970066
Quantity
96 tests
Datasheet
Datasheet
Recommended SLPI Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275627
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275628
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1320577
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SLPI products
: "Editor's Highlight: Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 156, Issue 2, pp. 438-454, (2018) (PubMed).: "Serum alarm antiproteases in systemic sclerosis patients." in: Human immunology, Vol. 78, Issue 9, pp. 559-564, (2018) (PubMed).
: "Secretory leukocyte protease inhibitor regulates human periodontal ligament cell production of pro-inflammatory cytokines." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 66, Issue 9, pp. 823-831, (2018) (PubMed).
: "Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells." in: PLoS ONE, Vol. 9, Issue 8, pp. e104223, (2015) (PubMed).
: "Activated microglia enhance neurogenesis via trypsinogen secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).
: "Secretory leukocyte protease inhibitor inhibits neutrophil apoptosis." in: Respirology (Carlton, Vic.), Vol. 16, Issue 2, pp. 300-7, (2011) (PubMed).
: "Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer." in: International journal of cancer. Journal international du cancer, Vol. 123, Issue 8, pp. 1787-96, (2008) (PubMed).
: "WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung." in: Respiratory research, Vol. 7, pp. 61, (2006) (PubMed).
: "Human immunodeficiency virus type 1 stimulates the expression and production of secretory leukocyte protease inhibitor (SLPI) in oral epithelial cells: a role for SLPI in innate mucosal immunity." in: Journal of virology, Vol. 79, Issue 10, pp. 6432-40, (2005) (PubMed).
: "Secretory leucoprotease inhibitor binds to NF-kappaB binding sites in monocytes and inhibits p65 binding." in: The Journal of experimental medicine, Vol. 202, Issue 12, pp. 1659-68, (2005) (PubMed).
Synonyms and alternative names related to SLPI
secretory leukocyte peptidase inhibitor (SLPI), secretory leukocyte peptidase inhibitor (Slpi), antileukoproteinase (LOC102174044), ALK1, ALP, BLPI, ckpi, HUSI, HUSI-I, MATN4, MPI, SLPI, WAP4, WFDC4Protein level used designations for SLPI
- HUSI-1
- WAP four-disulfide core domain protein 4
- antileukoproteinase
- mucus proteinase inhibitor
- protease inhibitor WAP4
- secretory leukocyte protease inhibitor (antileukoproteinase)
- seminal proteinase inhibitor
- ALP
- secretory leukocyte protease inhibitor
- matrilin 4
- secretory leukocyte peptidase inhibitor
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