SLC7A11 Products
(Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
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This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011].
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Featured SLC7A11 Categories
SLC7A11 Antibodies
High quality antibodies with extensive validation data.
SLC7A11 ELISA Kits
Reliable ELISA kits for a wide range of species.
SLC7A11 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLC7A11 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (10)
Cat. No.
ABIN190899
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, FM, IP
Validations
- (4)
Cat. No.
ABIN6655336
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (4)
Cat. No.
ABIN7043751
Quantity
25 μL
Datasheet
Datasheet
Recommended SLC7A11 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970357
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959627
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959628
Quantity
96 tests
Datasheet
Datasheet
Recommended SLC7A11 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491739
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7092733
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1320520
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SLC7A11 products
: "Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 25, Issue 8, pp. 2471-2482, (2019) (PubMed).: "Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension." in: American journal of respiratory cell and molecular biology, (2019) (PubMed).
: "xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain." in: Molecular pain, Vol. 15, pp. 1744806918822185, (2019) (PubMed).
: "mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis." in: Cell death and differentiation, (2019) (PubMed).
: "Influx rate of 18F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts." in: European journal of nuclear medicine and molecular imaging, Vol. 46, Issue 10, pp. 2190-2198, (2019) (PubMed).
: "[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 55, (2018) (PubMed).
: "Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain." in: Molecular pain, Vol. 14, pp. 1744806918776467, (2018) (PubMed).
: "RGS4 deficit in prefrontal cortex contributes to the behaviors related to schizophrenia via system xc--mediated glutamatergic dysfunction in mice." in: Theranostics, Vol. 8, Issue 17, pp. 4781-4794, (2018) (PubMed).
: "Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice." in: Neurobiology of aging, Vol. 71, pp. 241-254, (2018) (PubMed).
: "Characterization of the cystine/glutamate antiporter in cultured Bergmann glia cells." in: Neurochemistry international, (2017) (PubMed).
Synonyms and alternative names related to SLC7A11
solute carrier family 7 member 11 (SLC7A11), solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (SLC7A11), solute carrier family 7 member 11 (Slc7a11), solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 (Slc7a11), 9930009M05Rik, AI451155, CCBR1, DKFZp468E122, SLC7A11, sut, xCTProtein level used designations for SLC7A11
- solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
- cystine/glutamate transporter
- solute carrier family 7, member 11
- Cystine/glutamate transporter
- cystine/glutamate transporter-like
- solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- amino acid transport system xc-
- calcium channel blocker resistance protein CCBR1
- solute carrier family 7 member 11
- solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
- cysteine/glutamate transporter
- sodium independent anionic amino acid transport system
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