SLC46A1 Products
(Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1))
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This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia, hypoimmunoglobulinemia, and recurrent infections. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011].
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Featured SLC46A1 Categories
SLC46A1 Antibodies
High quality antibodies with extensive validation data.
SLC46A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SLC46A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7166588
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN768542
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6741754
Quantity
100 μL
Datasheet
Datasheet
Recommended SLC46A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1330511
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3117461
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3123723
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to SLC46A1
solute carrier family 46 member 1 (SLC46A1), solute carrier family 46 (folate transporter), member 1 (slc46a1), solute carrier family 46 member 1 (Slc46a1), solute carrier family 46, member 1 (Slc46a1), 1110002C08Rik, D11Ertd18e, G21, HCP1, PCFT, Pcft, RGD1309472, TRPEProtein level used designations for SLC46A1
- solute carrier family 46, member 1
- solute carrier family 46 (folate transporter), member 1
- proton-coupled folate transporter-like
- heme carrier protein 1
- proton-coupled folate transporter
- PCFT/HCP1
- retinal pigment epithelilum transporter
- retinal pigment epithelium transporter
- solute carrier family 46 member 1
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